Rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa

According to the International Diabetes Federation there are at least 285 million people suffering from diabetes mellitus (DM) in the world, and by2030 this figure is likely to be more than 438 million people, mostly at the expense of patients with type 2 diabetes (T2DM) . According to the Stateregi...

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Autores principales:	Alexander Sergeevich Ametov, Ekaterina Vladimirovna Karpova
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2011
Materias:	diabetes mellitus combined therapy dpp-4 inhibitors Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/fecf93a8df3740dd80bd161546a97627
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spelling	oai:doaj.org-article:fecf93a8df3740dd80bd161546a976272021-11-14T09:00:16ZRannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa2072-03512072-037810.14341/2072-0351-6229https://doaj.org/article/fecf93a8df3740dd80bd161546a976272011-09-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6229https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378According to the International Diabetes Federation there are at least 285 million people suffering from diabetes mellitus (DM) in the world, and by2030 this figure is likely to be more than 438 million people, mostly at the expense of patients with type 2 diabetes (T2DM) . According to the Stateregister of diabetic patients on January 1, 2010 in Russia there are over 3.1 million patients with diabetes, among them 2,822,634 with T2DM.Diabetes is the leading cause of blindness in adults aged 20-74 years, non-traumatic lower limb amputations, and the last stage of kidney failure.More than 50-80% of patients with diabetes die of cardiovascular complications. In addition, people with T2DM live almost 10 years less than peoplewithout diabetes. With regard to the effective management of diabetes, there is strong evidence showing that improved glycemic control can significantlyreduce the risk of late complications of the disease. The project Consensus of the Russian Association of Endocrinologists (RAE) was publishedin 2011. The main emphasis in this project is on individual approach to treatment of the patient. According to the recommendations of experts RAEmonotherapy antidiabetic agents in combination with lifestyle modification is possible only at the initial level of HbA1c 6,5-7,5%. At the initial levelof HbA1c 7,6-9,0% combined therapy should be started immediately, and at the level of HbA1c above 9.0% insulin therapy should be assigned. It isimportant to note that the priority in the choice of treatment should be safety and efficacy. For one of the most efficient is the combination of metforminand DPP-4 inhibitorAlexander Sergeevich AmetovEkaterina Vladimirovna KarpovaEndocrinology Research Centrearticlediabetes mellituscombined therapydpp-4 inhibitorsNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 14, Iss 3, Pp 80-83 (2011)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes mellitus combined therapy dpp-4 inhibitors Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	diabetes mellitus combined therapy dpp-4 inhibitors Nutritional diseases. Deficiency diseases RC620-627 Alexander Sergeevich Ametov Ekaterina Vladimirovna Karpova Rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa
description	According to the International Diabetes Federation there are at least 285 million people suffering from diabetes mellitus (DM) in the world, and by2030 this figure is likely to be more than 438 million people, mostly at the expense of patients with type 2 diabetes (T2DM) . According to the Stateregister of diabetic patients on January 1, 2010 in Russia there are over 3.1 million patients with diabetes, among them 2,822,634 with T2DM.Diabetes is the leading cause of blindness in adults aged 20-74 years, non-traumatic lower limb amputations, and the last stage of kidney failure.More than 50-80% of patients with diabetes die of cardiovascular complications. In addition, people with T2DM live almost 10 years less than peoplewithout diabetes. With regard to the effective management of diabetes, there is strong evidence showing that improved glycemic control can significantlyreduce the risk of late complications of the disease. The project Consensus of the Russian Association of Endocrinologists (RAE) was publishedin 2011. The main emphasis in this project is on individual approach to treatment of the patient. According to the recommendations of experts RAEmonotherapy antidiabetic agents in combination with lifestyle modification is possible only at the initial level of HbA1c 6,5-7,5%. At the initial levelof HbA1c 7,6-9,0% combined therapy should be started immediately, and at the level of HbA1c above 9.0% insulin therapy should be assigned. It isimportant to note that the priority in the choice of treatment should be safety and efficacy. For one of the most efficient is the combination of metforminand DPP-4 inhibitor
format	article
author	Alexander Sergeevich Ametov Ekaterina Vladimirovna Karpova
author_facet	Alexander Sergeevich Ametov Ekaterina Vladimirovna Karpova
author_sort	Alexander Sergeevich Ametov
title	Rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa
title_short	Rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa
title_full	Rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa
title_fullStr	Rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa
title_full_unstemmed	Rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa
title_sort	rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa
publisher	Endocrinology Research Centre
publishDate	2011
url	https://doaj.org/article/fecf93a8df3740dd80bd161546a97627
work_keys_str_mv	AT alexandersergeevichametov rannyayakombinirovannayaterapiyaprisakharnomdiabete2tipa AT ekaterinavladimirovnakarpova rannyayakombinirovannayaterapiyaprisakharnomdiabete2tipa
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Rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa

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