Consistent RNA sequencing contamination in GTEx and other data sets
Sample contamination has been reported in high throughput RNA sequencing. Here the authors analyze the RNA sequencing data from the Genotype-Tissue Expression project and describe how highly expressed, tissue specific genes contaminate across samples, which is corroborated in other data sets.
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Nature Portfolio
2020
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oai:doaj.org-article:fede4787d2dc40708b7ce5f17be141ab2021-12-02T15:39:21ZConsistent RNA sequencing contamination in GTEx and other data sets10.1038/s41467-020-15821-92041-1723https://doaj.org/article/fede4787d2dc40708b7ce5f17be141ab2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15821-9https://doaj.org/toc/2041-1723Sample contamination has been reported in high throughput RNA sequencing. Here the authors analyze the RNA sequencing data from the Genotype-Tissue Expression project and describe how highly expressed, tissue specific genes contaminate across samples, which is corroborated in other data sets.Tim O. NieuwenhuisStephanie Y. YangRohan X. VermaVamsee PillalamarriDan E. ArkingAvi Z. RosenbergMatthew N. McCallMarc K. HalushkaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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Science Q Tim O. Nieuwenhuis Stephanie Y. Yang Rohan X. Verma Vamsee Pillalamarri Dan E. Arking Avi Z. Rosenberg Matthew N. McCall Marc K. Halushka Consistent RNA sequencing contamination in GTEx and other data sets |
description |
Sample contamination has been reported in high throughput RNA sequencing. Here the authors analyze the RNA sequencing data from the Genotype-Tissue Expression project and describe how highly expressed, tissue specific genes contaminate across samples, which is corroborated in other data sets. |
format |
article |
author |
Tim O. Nieuwenhuis Stephanie Y. Yang Rohan X. Verma Vamsee Pillalamarri Dan E. Arking Avi Z. Rosenberg Matthew N. McCall Marc K. Halushka |
author_facet |
Tim O. Nieuwenhuis Stephanie Y. Yang Rohan X. Verma Vamsee Pillalamarri Dan E. Arking Avi Z. Rosenberg Matthew N. McCall Marc K. Halushka |
author_sort |
Tim O. Nieuwenhuis |
title |
Consistent RNA sequencing contamination in GTEx and other data sets |
title_short |
Consistent RNA sequencing contamination in GTEx and other data sets |
title_full |
Consistent RNA sequencing contamination in GTEx and other data sets |
title_fullStr |
Consistent RNA sequencing contamination in GTEx and other data sets |
title_full_unstemmed |
Consistent RNA sequencing contamination in GTEx and other data sets |
title_sort |
consistent rna sequencing contamination in gtex and other data sets |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/fede4787d2dc40708b7ce5f17be141ab |
work_keys_str_mv |
AT timonieuwenhuis consistentrnasequencingcontaminationingtexandotherdatasets AT stephanieyyang consistentrnasequencingcontaminationingtexandotherdatasets AT rohanxverma consistentrnasequencingcontaminationingtexandotherdatasets AT vamseepillalamarri consistentrnasequencingcontaminationingtexandotherdatasets AT danearking consistentrnasequencingcontaminationingtexandotherdatasets AT avizrosenberg consistentrnasequencingcontaminationingtexandotherdatasets AT matthewnmccall consistentrnasequencingcontaminationingtexandotherdatasets AT marckhalushka consistentrnasequencingcontaminationingtexandotherdatasets |
_version_ |
1718385969676156928 |