Consistent RNA sequencing contamination in GTEx and other data sets

Sample contamination has been reported in high throughput RNA sequencing. Here the authors analyze the RNA sequencing data from the Genotype-Tissue Expression project and describe how highly expressed, tissue specific genes contaminate across samples, which is corroborated in other data sets.

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Bibliographic Details
Main Authors:	Tim O. Nieuwenhuis, Stephanie Y. Yang, Rohan X. Verma, Vamsee Pillalamarri, Dan E. Arking, Avi Z. Rosenberg, Matthew N. McCall, Marc K. Halushka
Format:	article
Language:	EN
Published:	Nature Portfolio 2020
Subjects:	Science Q
Online Access:	https://doaj.org/article/fede4787d2dc40708b7ce5f17be141ab
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id	oai:doaj.org-article:fede4787d2dc40708b7ce5f17be141ab
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spelling	oai:doaj.org-article:fede4787d2dc40708b7ce5f17be141ab2021-12-02T15:39:21ZConsistent RNA sequencing contamination in GTEx and other data sets10.1038/s41467-020-15821-92041-1723https://doaj.org/article/fede4787d2dc40708b7ce5f17be141ab2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15821-9https://doaj.org/toc/2041-1723Sample contamination has been reported in high throughput RNA sequencing. Here the authors analyze the RNA sequencing data from the Genotype-Tissue Expression project and describe how highly expressed, tissue specific genes contaminate across samples, which is corroborated in other data sets.Tim O. NieuwenhuisStephanie Y. YangRohan X. VermaVamsee PillalamarriDan E. ArkingAvi Z. RosenbergMatthew N. McCallMarc K. HalushkaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tim O. Nieuwenhuis Stephanie Y. Yang Rohan X. Verma Vamsee Pillalamarri Dan E. Arking Avi Z. Rosenberg Matthew N. McCall Marc K. Halushka Consistent RNA sequencing contamination in GTEx and other data sets
description	Sample contamination has been reported in high throughput RNA sequencing. Here the authors analyze the RNA sequencing data from the Genotype-Tissue Expression project and describe how highly expressed, tissue specific genes contaminate across samples, which is corroborated in other data sets.
format	article
author	Tim O. Nieuwenhuis Stephanie Y. Yang Rohan X. Verma Vamsee Pillalamarri Dan E. Arking Avi Z. Rosenberg Matthew N. McCall Marc K. Halushka
author_facet	Tim O. Nieuwenhuis Stephanie Y. Yang Rohan X. Verma Vamsee Pillalamarri Dan E. Arking Avi Z. Rosenberg Matthew N. McCall Marc K. Halushka
author_sort	Tim O. Nieuwenhuis
title	Consistent RNA sequencing contamination in GTEx and other data sets
title_short	Consistent RNA sequencing contamination in GTEx and other data sets
title_full	Consistent RNA sequencing contamination in GTEx and other data sets
title_fullStr	Consistent RNA sequencing contamination in GTEx and other data sets
title_full_unstemmed	Consistent RNA sequencing contamination in GTEx and other data sets
title_sort	consistent rna sequencing contamination in gtex and other data sets
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/fede4787d2dc40708b7ce5f17be141ab
work_keys_str_mv	AT timonieuwenhuis consistentrnasequencingcontaminationingtexandotherdatasets AT stephanieyyang consistentrnasequencingcontaminationingtexandotherdatasets AT rohanxverma consistentrnasequencingcontaminationingtexandotherdatasets AT vamseepillalamarri consistentrnasequencingcontaminationingtexandotherdatasets AT danearking consistentrnasequencingcontaminationingtexandotherdatasets AT avizrosenberg consistentrnasequencingcontaminationingtexandotherdatasets AT matthewnmccall consistentrnasequencingcontaminationingtexandotherdatasets AT marckhalushka consistentrnasequencingcontaminationingtexandotherdatasets
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Consistent RNA sequencing contamination in GTEx and other data sets

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