Self-reported psychopathology and health-related quality of life in heroin users treated with methadone

Ying-Zai Chen,1 Wei-Lieh Huang,1,2,5 Jia-Chi Shan,4,5 Yu-Hsuan Lin,1&ndash;3,5 Hung-Chieh Wu Chang,1 Li-Ren Chang1,61Department of Psychiatry, National Taiwan University Hospital, Yun-Lin Branch, 2Institute of Brain Science, National Yang-Ming University, 3Sleep Research Center, National Yan...

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Autores principales:	Chen YZ, Huang WL, Shan JC, Lin YH, Wu Chang HC, Chang LR
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/fee3b6663a3d461ca6397e13f3216d55
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spelling	oai:doaj.org-article:fee3b6663a3d461ca6397e13f3216d552021-12-02T05:19:23ZSelf-reported psychopathology and health-related quality of life in heroin users treated with methadone1176-63281178-2021https://doaj.org/article/fee3b6663a3d461ca6397e13f3216d552012-12-01T00:00:00Zhttp://www.dovepress.com/self-reported-psychopathology-and-health-related-quality-of-life-in-he-a11819https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Ying-Zai Chen,1 Wei-Lieh Huang,1,2,5 Jia-Chi Shan,4,5 Yu-Hsuan Lin,1&ndash;3,5 Hung-Chieh Wu Chang,1 Li-Ren Chang1,61Department of Psychiatry, National Taiwan University Hospital, Yun-Lin Branch, 2Institute of Brain Science, National Yang-Ming University, 3Sleep Research Center, National Yang-Ming University, 4Department of Psychiatry, Cathay General Hospital, Taipei, 5Department of Psychiatry, National Taiwan University Hospital, 6Department of Psychiatry, Medical College, National Taiwan University, Taipei, TaiwanBackground: Health-related quality of life (HRQoL) remains poor among heroin users, even after being treated with methadone. Evidence regarding self-reported psychopathology and HRQoL in heroin users is also limited. The present study aimed to investigate the association between self-reported psychopathology and HRQoL in Asian heroin users treated with methadone.Methods: Thirty-nine heroin users treated with methadone and 39 healthy controls were recruited. Both groups self-reported on demographic data, the Brief Symptom Rating Scale, EuroQoL-5D, and World Health Organization Questionnaire on Quality of Life: Short Form. We compared clinical characteristics, psychopathology, and HRQoL between the two study groups. Correlation and regression analyses were conducted to explore the association between psychopathology and HRQoL in the heroin user group.Results: Heroin users had more psychopathology and worse HRQoL than healthy controls. The HRQoL of heroin users had significant correlations with Brief Symptom Rating Scale scores. HRQoL could be predicted by depression, anxiety, paranoia, and additional symptoms (ie, poor appetite and sleep difficulties) independently.Conclusion: Self-reported psychopathology, depression, anxiety, paranoia, poor appetite, and sleep difficulties had a negative impact on each domain of HRQoL among heroin users treated with methadone. The importance of the environmental domain of HRQoL is discussed. Clinicians should recognize comorbid psychiatric symptoms early on to improve HRQoL in heroin users.Keywords: heroin abuse, Brief Symptom Rating Scale, World Health Organization questionnaire on quality of lifeChen YZHuang WLShan JCLin YHWu Chang HCChang LRDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 41-48 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Chen YZ Huang WL Shan JC Lin YH Wu Chang HC Chang LR Self-reported psychopathology and health-related quality of life in heroin users treated with methadone
description	Ying-Zai Chen,1 Wei-Lieh Huang,1,2,5 Jia-Chi Shan,4,5 Yu-Hsuan Lin,1&ndash;3,5 Hung-Chieh Wu Chang,1 Li-Ren Chang1,61Department of Psychiatry, National Taiwan University Hospital, Yun-Lin Branch, 2Institute of Brain Science, National Yang-Ming University, 3Sleep Research Center, National Yang-Ming University, 4Department of Psychiatry, Cathay General Hospital, Taipei, 5Department of Psychiatry, National Taiwan University Hospital, 6Department of Psychiatry, Medical College, National Taiwan University, Taipei, TaiwanBackground: Health-related quality of life (HRQoL) remains poor among heroin users, even after being treated with methadone. Evidence regarding self-reported psychopathology and HRQoL in heroin users is also limited. The present study aimed to investigate the association between self-reported psychopathology and HRQoL in Asian heroin users treated with methadone.Methods: Thirty-nine heroin users treated with methadone and 39 healthy controls were recruited. Both groups self-reported on demographic data, the Brief Symptom Rating Scale, EuroQoL-5D, and World Health Organization Questionnaire on Quality of Life: Short Form. We compared clinical characteristics, psychopathology, and HRQoL between the two study groups. Correlation and regression analyses were conducted to explore the association between psychopathology and HRQoL in the heroin user group.Results: Heroin users had more psychopathology and worse HRQoL than healthy controls. The HRQoL of heroin users had significant correlations with Brief Symptom Rating Scale scores. HRQoL could be predicted by depression, anxiety, paranoia, and additional symptoms (ie, poor appetite and sleep difficulties) independently.Conclusion: Self-reported psychopathology, depression, anxiety, paranoia, poor appetite, and sleep difficulties had a negative impact on each domain of HRQoL among heroin users treated with methadone. The importance of the environmental domain of HRQoL is discussed. Clinicians should recognize comorbid psychiatric symptoms early on to improve HRQoL in heroin users.Keywords: heroin abuse, Brief Symptom Rating Scale, World Health Organization questionnaire on quality of life
format	article
author	Chen YZ Huang WL Shan JC Lin YH Wu Chang HC Chang LR
author_facet	Chen YZ Huang WL Shan JC Lin YH Wu Chang HC Chang LR
author_sort	Chen YZ
title	Self-reported psychopathology and health-related quality of life in heroin users treated with methadone
title_short	Self-reported psychopathology and health-related quality of life in heroin users treated with methadone
title_full	Self-reported psychopathology and health-related quality of life in heroin users treated with methadone
title_fullStr	Self-reported psychopathology and health-related quality of life in heroin users treated with methadone
title_full_unstemmed	Self-reported psychopathology and health-related quality of life in heroin users treated with methadone
title_sort	self-reported psychopathology and health-related quality of life in heroin users treated with methadone
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/fee3b6663a3d461ca6397e13f3216d55
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Self-reported psychopathology and health-related quality of life in heroin users treated with methadone

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