Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery

Susmita Aryal,1,* Hyungkyu Park,1,* James F Leary,2 Jaehong Key11Department of Biomedical Engineering, Yonsei University, Wonju, Gangwon-do 26493, South Korea; 2Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47906, USACorrespondence: Jaehong KeyDepartment of Biomedica...

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Autores principales:	Aryal S, Park H, Leary JF, Key J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Fabrication Lithography Cancer Advanced manufacturing method Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/fef4938612384f778b8df03e5ccb471c
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spelling	oai:doaj.org-article:fef4938612384f778b8df03e5ccb471c2021-12-02T03:37:27ZTop-down fabrication-based nano/microparticles for molecular imaging and drug delivery1178-2013https://doaj.org/article/fef4938612384f778b8df03e5ccb471c2019-08-01T00:00:00Zhttps://www.dovepress.com/top-down-fabrication-based-nanomicroparticles-for-molecular-imaging-an-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Susmita Aryal,1,* Hyungkyu Park,1,* James F Leary,2 Jaehong Key11Department of Biomedical Engineering, Yonsei University, Wonju, Gangwon-do 26493, South Korea; 2Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47906, USACorrespondence: Jaehong KeyDepartment of Biomedical Engineering, Yonsei University, 1 Yonseidae-gil Wonju, Gangwon-do 26493, South KoreaTel +82 33 760 2857Fax +82 33 760 2919Email jkey@yonsei.ac.kr*These authors contributed equally to this workAbstract: Recent breakthroughs in nanoparticle research have led to improved drug delivery and have overcome problems associated with normal drug delivery methods. Optimizing the design of nanoparticles in terms of controlled size, shape, and surface chemistry of nanoparticles can maximize the therapeutic efficacy. To maximize therapeutic effects, advanced formulation and fabrication methods have been developed. Biomedical applications of nanoparticles produced using the new fabrication techniques, including drug delivery and molecular imaging, have been widely explored. This review highlights the simple and versatile manufacturing techniques that can be used in the development of new types of nanoparticles that have strictly controlled physiochemical properties and their multifaceted advantages in drug delivery and molecular imaging.Keywords: fabrication, lithography, cancer, advanced manufacturing methodAryal SPark HLeary JFKey JDove Medical PressarticleFabricationLithographyCancerAdvanced manufacturing methodMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 14, Pp 6631-6644 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Fabrication Lithography Cancer Advanced manufacturing method Medicine (General) R5-920
spellingShingle	Fabrication Lithography Cancer Advanced manufacturing method Medicine (General) R5-920 Aryal S Park H Leary JF Key J Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery
description	Susmita Aryal,1,* Hyungkyu Park,1,* James F Leary,2 Jaehong Key11Department of Biomedical Engineering, Yonsei University, Wonju, Gangwon-do 26493, South Korea; 2Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47906, USACorrespondence: Jaehong KeyDepartment of Biomedical Engineering, Yonsei University, 1 Yonseidae-gil Wonju, Gangwon-do 26493, South KoreaTel +82 33 760 2857Fax +82 33 760 2919Email jkey@yonsei.ac.kr*These authors contributed equally to this workAbstract: Recent breakthroughs in nanoparticle research have led to improved drug delivery and have overcome problems associated with normal drug delivery methods. Optimizing the design of nanoparticles in terms of controlled size, shape, and surface chemistry of nanoparticles can maximize the therapeutic efficacy. To maximize therapeutic effects, advanced formulation and fabrication methods have been developed. Biomedical applications of nanoparticles produced using the new fabrication techniques, including drug delivery and molecular imaging, have been widely explored. This review highlights the simple and versatile manufacturing techniques that can be used in the development of new types of nanoparticles that have strictly controlled physiochemical properties and their multifaceted advantages in drug delivery and molecular imaging.Keywords: fabrication, lithography, cancer, advanced manufacturing method
format	article
author	Aryal S Park H Leary JF Key J
author_facet	Aryal S Park H Leary JF Key J
author_sort	Aryal S
title	Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery
title_short	Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery
title_full	Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery
title_fullStr	Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery
title_full_unstemmed	Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery
title_sort	top-down fabrication-based nano/microparticles for molecular imaging and drug delivery
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/fef4938612384f778b8df03e5ccb471c
work_keys_str_mv	AT aryals topdownfabricationbasednanomicroparticlesformolecularimaginganddrugdelivery AT parkh topdownfabricationbasednanomicroparticlesformolecularimaginganddrugdelivery AT learyjf topdownfabricationbasednanomicroparticlesformolecularimaginganddrugdelivery AT keyj topdownfabricationbasednanomicroparticlesformolecularimaginganddrugdelivery
_version_	1718401710135705600

Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery

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