The cyclooxygenase-1/mPGES-1/endothelial prostaglandin EP4 receptor pathway constrains myocardial ischemia-reperfusion injury

The cyclooxygenase-1/mPGES-1/endothelial prostaglandin EP4 receptor pathway constrains myocardial ischemia-reperfusion injury

The use of nonsteroidal anti-inflammatory drugs inhibiting COX-1/2 is associated with an increased risk of heart failure. Here the authors show that mPGES-1, a therapeutic target downstream of COX enzymes, protects from cardiac ischemia/reperfusion injury, limiting leukocyte-endothelial interactions...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Liyuan Zhu, Chuansheng Xu, Xingyu Huo, Huifeng Hao, Qing Wan, Hong Chen, Xu Zhang, Richard M. Breyer, Yu Huang, Xuetao Cao, De-Pei Liu, Garret A. FitzGerald, Miao Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/fef88a14e9b647e0a6efff38e6e014ef
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares