Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis

Anne Huhtala,1 Juhani Pietilä,1,2 Petri Mäkinen,1,2 Hannu Uusitalo1–3 1Silmäasema Eye Hospital, 2SILK, Department of Ophthalmology, School of Medicine, University of Tampere, 3TAUH Eye Center, Tampere University Hospital, Tampere, Finland Purpose: The aim of th...

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Autores principales: Huhtala A, Pietilä J, Mäkinen P, Uusitalo H
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Publicado: Dove Medical Press 2016
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spelling oai:doaj.org-article:fefaec0f708d4ca5ba6cf8821695b8eb2021-12-02T08:42:10ZFemtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis1177-5483https://doaj.org/article/fefaec0f708d4ca5ba6cf8821695b8eb2016-03-01T00:00:00Zhttps://www.dovepress.com/femtosecond-lasers-for-laser-in-situ-keratomileusis-a-systematic-revie-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Anne Huhtala,1 Juhani Pietilä,1,2 Petri Mäkinen,1,2 Hannu Uusitalo1–3 1Silmäasema Eye Hospital, 2SILK, Department of Ophthalmology, School of Medicine, University of Tampere, 3TAUH Eye Center, Tampere University Hospital, Tampere, Finland Purpose: The aim of this study was to review and meta-analyze whether there are differences between reported femtosecond (FS) lasers for laser-assisted in situ keratomileusis (LASIK) in terms of efficacy, predictability, and safety as primary outcomes and corneal flap thickness measurements and pre- and postoperative complications as secondary outcomes.Methods: A comprehensive literature search of PubMed, Science Direct, Scopus, and Cochrane CENTRAL Trials Library databases was conducted to identify the relevant prospective randomized controlled trials of FS lasers for LASIK. Thirty-one articles describing a total of 5,404 eyes were included.Results: Based on efficacy, IntraLase FS 10 and 30 kHz gave the best results. Based on predictability and safety, there were no differences between various FS lasers. FEMTO LDV and IntraLase FS 60 kHz produced the most accurate flap thicknesses. IntraLase and Wavelight SF200 had the fewest intraoperative complications. IntraLase, Visumax, and Wavelight FS200 had the most seldom postoperative complications.Conclusion: There were dissimilarities between different FS lasers based on efficacy and intraoperative and postoperative complications. All FS lasers were predictable and safe for making corneal flaps in LASIK. Keywords: femtosecond laser, laser in situ keratomileusis, LASIK, meta-analysisHuhtala APietilä JMäkinen PUusitalo HDove Medical PressarticleFemtosecond laserlaser in situ keratomileusisLASIKOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 393-404 (2016)
institution DOAJ
collection DOAJ
language EN
topic Femtosecond laser
laser in situ keratomileusis
LASIK
Ophthalmology
RE1-994
spellingShingle Femtosecond laser
laser in situ keratomileusis
LASIK
Ophthalmology
RE1-994
Huhtala A
Pietilä J
Mäkinen P
Uusitalo H
Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
description Anne Huhtala,1 Juhani Pietilä,1,2 Petri Mäkinen,1,2 Hannu Uusitalo1–3 1Silmäasema Eye Hospital, 2SILK, Department of Ophthalmology, School of Medicine, University of Tampere, 3TAUH Eye Center, Tampere University Hospital, Tampere, Finland Purpose: The aim of this study was to review and meta-analyze whether there are differences between reported femtosecond (FS) lasers for laser-assisted in situ keratomileusis (LASIK) in terms of efficacy, predictability, and safety as primary outcomes and corneal flap thickness measurements and pre- and postoperative complications as secondary outcomes.Methods: A comprehensive literature search of PubMed, Science Direct, Scopus, and Cochrane CENTRAL Trials Library databases was conducted to identify the relevant prospective randomized controlled trials of FS lasers for LASIK. Thirty-one articles describing a total of 5,404 eyes were included.Results: Based on efficacy, IntraLase FS 10 and 30 kHz gave the best results. Based on predictability and safety, there were no differences between various FS lasers. FEMTO LDV and IntraLase FS 60 kHz produced the most accurate flap thicknesses. IntraLase and Wavelight SF200 had the fewest intraoperative complications. IntraLase, Visumax, and Wavelight FS200 had the most seldom postoperative complications.Conclusion: There were dissimilarities between different FS lasers based on efficacy and intraoperative and postoperative complications. All FS lasers were predictable and safe for making corneal flaps in LASIK. Keywords: femtosecond laser, laser in situ keratomileusis, LASIK, meta-analysis
format article
author Huhtala A
Pietilä J
Mäkinen P
Uusitalo H
author_facet Huhtala A
Pietilä J
Mäkinen P
Uusitalo H
author_sort Huhtala A
title Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_short Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_full Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_fullStr Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_full_unstemmed Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_sort femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/fefaec0f708d4ca5ba6cf8821695b8eb
work_keys_str_mv AT huhtalaa femtosecondlasersforlaserinsitukeratomileusisasystematicreviewandmetaanalysis
AT pietilaj femtosecondlasersforlaserinsitukeratomileusisasystematicreviewandmetaanalysis
AT makinenp femtosecondlasersforlaserinsitukeratomileusisasystematicreviewandmetaanalysis
AT uusitaloh femtosecondlasersforlaserinsitukeratomileusisasystematicreviewandmetaanalysis
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