Acral lentiginous melanoma in situ: dermoscopic features and management strategy

Abstract Diagnosis of acral lentiginous melanoma in situ (ALMIS) is challenging. However, data regarding ALMIS are limited in the literature. The aim of this study was to investigate the clinical and dermoscopic features of ALMIS on palmoplantar surfaces. Patients with ALMIS and available dermoscopi...

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Autores principales:	Byeol Han, Keunyoung Hur, Jungyoon Ohn, Sophie Soyeon Lim, Je-Ho Mun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ff038bbec203486990d3bc2c50ade808
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spelling	oai:doaj.org-article:ff038bbec203486990d3bc2c50ade8082021-12-02T16:09:10ZAcral lentiginous melanoma in situ: dermoscopic features and management strategy10.1038/s41598-020-77425-z2045-2322https://doaj.org/article/ff038bbec203486990d3bc2c50ade8082020-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-77425-zhttps://doaj.org/toc/2045-2322Abstract Diagnosis of acral lentiginous melanoma in situ (ALMIS) is challenging. However, data regarding ALMIS are limited in the literature. The aim of this study was to investigate the clinical and dermoscopic features of ALMIS on palmoplantar surfaces. Patients with ALMIS and available dermoscopic images were retrospectively reviewed at our institution between January 2013 and February 2020. Clinical and dermoscopic features were analysed and compared between small (< 15 mm) and large (≥ 15 mm) ALMIS. Twenty-one patients with ALMIS were included in this study. Mean patient age was 58.5 (range 39–76) years; most lesions were located on the sole (90.5%). The mean maximal diameter was 19.9 ± 13.7 mm (mean ± standard deviation). Statistical analysis of dermoscopic features revealed that parallel ridge patterns (54.5% vs. 100%, P = 0.035), irregular diffuse pigmentation (27.3% vs. 100%, P = 0.001) and grey colour (18.2% vs. 90%, P = 0.002) were significantly less frequent in small lesions than in large lesions. We have also illustrated two unique cases of small ALMIS; their evolution and follow-up dermoscopic examination are provided. In conclusion, this study described detailed dermoscopic findings of ALMIS. Based on the present study and a review of the literature, we proposed a dermoscopic algorithm for the diagnosis of ALMIS.Byeol HanKeunyoung HurJungyoon OhnSophie Soyeon LimJe-Ho MunNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Byeol Han Keunyoung Hur Jungyoon Ohn Sophie Soyeon Lim Je-Ho Mun Acral lentiginous melanoma in situ: dermoscopic features and management strategy
description	Abstract Diagnosis of acral lentiginous melanoma in situ (ALMIS) is challenging. However, data regarding ALMIS are limited in the literature. The aim of this study was to investigate the clinical and dermoscopic features of ALMIS on palmoplantar surfaces. Patients with ALMIS and available dermoscopic images were retrospectively reviewed at our institution between January 2013 and February 2020. Clinical and dermoscopic features were analysed and compared between small (< 15 mm) and large (≥ 15 mm) ALMIS. Twenty-one patients with ALMIS were included in this study. Mean patient age was 58.5 (range 39–76) years; most lesions were located on the sole (90.5%). The mean maximal diameter was 19.9 ± 13.7 mm (mean ± standard deviation). Statistical analysis of dermoscopic features revealed that parallel ridge patterns (54.5% vs. 100%, P = 0.035), irregular diffuse pigmentation (27.3% vs. 100%, P = 0.001) and grey colour (18.2% vs. 90%, P = 0.002) were significantly less frequent in small lesions than in large lesions. We have also illustrated two unique cases of small ALMIS; their evolution and follow-up dermoscopic examination are provided. In conclusion, this study described detailed dermoscopic findings of ALMIS. Based on the present study and a review of the literature, we proposed a dermoscopic algorithm for the diagnosis of ALMIS.
format	article
author	Byeol Han Keunyoung Hur Jungyoon Ohn Sophie Soyeon Lim Je-Ho Mun
author_facet	Byeol Han Keunyoung Hur Jungyoon Ohn Sophie Soyeon Lim Je-Ho Mun
author_sort	Byeol Han
title	Acral lentiginous melanoma in situ: dermoscopic features and management strategy
title_short	Acral lentiginous melanoma in situ: dermoscopic features and management strategy
title_full	Acral lentiginous melanoma in situ: dermoscopic features and management strategy
title_fullStr	Acral lentiginous melanoma in situ: dermoscopic features and management strategy
title_full_unstemmed	Acral lentiginous melanoma in situ: dermoscopic features and management strategy
title_sort	acral lentiginous melanoma in situ: dermoscopic features and management strategy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/ff038bbec203486990d3bc2c50ade808
work_keys_str_mv	AT byeolhan acrallentiginousmelanomainsitudermoscopicfeaturesandmanagementstrategy AT keunyounghur acrallentiginousmelanomainsitudermoscopicfeaturesandmanagementstrategy AT jungyoonohn acrallentiginousmelanomainsitudermoscopicfeaturesandmanagementstrategy AT sophiesoyeonlim acrallentiginousmelanomainsitudermoscopicfeaturesandmanagementstrategy AT jehomun acrallentiginousmelanomainsitudermoscopicfeaturesandmanagementstrategy
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Acral lentiginous melanoma in situ: dermoscopic features and management strategy

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