An inner activation gate controls TMEM16F phospholipid scrambling

TMEM16F is an enigmatic Ca2 + -activated phospholipid scramblase (CaPLSase) that passively transports phospholipids. Here authors identify an inner activation gate and its disruption profoundly alters TMEM16F phospholipid permeation.

Guardado en:

Detalles Bibliográficos
Autores principales:	Trieu Le, Zhiguang Jia, Son C. Le, Yang Zhang, Jianhan Chen, Huanghe Yang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ff04ecc72037485988bec5dbf32407c6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ff04ecc72037485988bec5dbf32407c6
record_format	dspace
spelling	oai:doaj.org-article:ff04ecc72037485988bec5dbf32407c62021-12-02T17:01:51ZAn inner activation gate controls TMEM16F phospholipid scrambling10.1038/s41467-019-09778-72041-1723https://doaj.org/article/ff04ecc72037485988bec5dbf32407c62019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09778-7https://doaj.org/toc/2041-1723TMEM16F is an enigmatic Ca2 + -activated phospholipid scramblase (CaPLSase) that passively transports phospholipids. Here authors identify an inner activation gate and its disruption profoundly alters TMEM16F phospholipid permeation.Trieu LeZhiguang JiaSon C. LeYang ZhangJianhan ChenHuanghe YangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Trieu Le Zhiguang Jia Son C. Le Yang Zhang Jianhan Chen Huanghe Yang An inner activation gate controls TMEM16F phospholipid scrambling
description	TMEM16F is an enigmatic Ca2 + -activated phospholipid scramblase (CaPLSase) that passively transports phospholipids. Here authors identify an inner activation gate and its disruption profoundly alters TMEM16F phospholipid permeation.
format	article
author	Trieu Le Zhiguang Jia Son C. Le Yang Zhang Jianhan Chen Huanghe Yang
author_facet	Trieu Le Zhiguang Jia Son C. Le Yang Zhang Jianhan Chen Huanghe Yang
author_sort	Trieu Le
title	An inner activation gate controls TMEM16F phospholipid scrambling
title_short	An inner activation gate controls TMEM16F phospholipid scrambling
title_full	An inner activation gate controls TMEM16F phospholipid scrambling
title_fullStr	An inner activation gate controls TMEM16F phospholipid scrambling
title_full_unstemmed	An inner activation gate controls TMEM16F phospholipid scrambling
title_sort	inner activation gate controls tmem16f phospholipid scrambling
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ff04ecc72037485988bec5dbf32407c6
work_keys_str_mv	AT trieule aninneractivationgatecontrolstmem16fphospholipidscrambling AT zhiguangjia aninneractivationgatecontrolstmem16fphospholipidscrambling AT soncle aninneractivationgatecontrolstmem16fphospholipidscrambling AT yangzhang aninneractivationgatecontrolstmem16fphospholipidscrambling AT jianhanchen aninneractivationgatecontrolstmem16fphospholipidscrambling AT huangheyang aninneractivationgatecontrolstmem16fphospholipidscrambling AT trieule inneractivationgatecontrolstmem16fphospholipidscrambling AT zhiguangjia inneractivationgatecontrolstmem16fphospholipidscrambling AT soncle inneractivationgatecontrolstmem16fphospholipidscrambling AT yangzhang inneractivationgatecontrolstmem16fphospholipidscrambling AT jianhanchen inneractivationgatecontrolstmem16fphospholipidscrambling AT huangheyang inneractivationgatecontrolstmem16fphospholipidscrambling
_version_	1718382060453756928

An inner activation gate controls TMEM16F phospholipid scrambling

Ejemplares similares