Tyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.

Photosynthetic reaction centers from Blastochloris viridis possess Tyr-L162 located mid-way between the special pair chlorophyll (P) and the heme (heme3). While mutation of the tyrosine does not affect the kinetics of electron transfer from heme3 to P, recent time-resolved Laue diffraction studies r...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Hiroshi Ishikita
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ff06182029344a5797f16fd57f282b30
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ff06182029344a5797f16fd57f282b30
record_format	dspace
spelling	oai:doaj.org-article:ff06182029344a5797f16fd57f282b302021-11-18T07:35:50ZTyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.1932-620310.1371/journal.pone.0026808https://doaj.org/article/ff06182029344a5797f16fd57f282b302011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22039551/?tool=EBIhttps://doaj.org/toc/1932-6203Photosynthetic reaction centers from Blastochloris viridis possess Tyr-L162 located mid-way between the special pair chlorophyll (P) and the heme (heme3). While mutation of the tyrosine does not affect the kinetics of electron transfer from heme3 to P, recent time-resolved Laue diffraction studies reported displacement of Tyr-L162 in response to the formation of the photo-oxidized P(+•), implying a possible tyrosine deprotonation event. pK(a) values for Tyr-L162 were calculated using the corresponding crystal structures. Movement of deprotonated Tyr-L162 toward Thr-M185 was observed in P(+•) formation. It was associated with rearrangement of the H-bond network that proceeds to P via Thr-M185 and His-L168.Hiroshi IshikitaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 10, p e26808 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hiroshi Ishikita Tyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.
description	Photosynthetic reaction centers from Blastochloris viridis possess Tyr-L162 located mid-way between the special pair chlorophyll (P) and the heme (heme3). While mutation of the tyrosine does not affect the kinetics of electron transfer from heme3 to P, recent time-resolved Laue diffraction studies reported displacement of Tyr-L162 in response to the formation of the photo-oxidized P(+•), implying a possible tyrosine deprotonation event. pK(a) values for Tyr-L162 were calculated using the corresponding crystal structures. Movement of deprotonated Tyr-L162 toward Thr-M185 was observed in P(+•) formation. It was associated with rearrangement of the H-bond network that proceeds to P via Thr-M185 and His-L168.
format	article
author	Hiroshi Ishikita
author_facet	Hiroshi Ishikita
author_sort	Hiroshi Ishikita
title	Tyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.
title_short	Tyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.
title_full	Tyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.
title_fullStr	Tyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.
title_full_unstemmed	Tyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.
title_sort	tyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/ff06182029344a5797f16fd57f282b30
work_keys_str_mv	AT hiroshiishikita tyrosinedeprotonationandassociatedhydrogenbondrearrangementsinaphotosyntheticreactioncenter
_version_	1718423263529402368

Tyrosine deprotonation and associated hydrogen bond rearrangements in a photosynthetic reaction center.

Ejemplares similares