Conditional immortalization of human B cells by CD40 ligation.
It is generally assumed that human differentiated cells have a limited life-span and proliferation capacity in vivo, and that genetic modifications are a prerequisite for their immortalization in vitro. Here we readdress this issue, studying the long-term proliferation potential of human B cells. It...
Guardado en:
Autores principales: | Martina Wiesner, Caroline Zentz, Christine Mayr, Rainer Wimmer, Wolfgang Hammerschmidt, Reinhard Zeidler, Andreas Moosmann |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2008
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Materias: | |
Acceso en línea: | https://doaj.org/article/ff0fccc34347455bb1c0e05213fd2ec2 |
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