Nanotubular surface modification of metallic implants via electrochemical anodization technique

Lu-Ning Wang,1 Ming Jin,1 Yudong Zheng,1 Yueping Guan,1 Xin Lu,1 Jing-Li Luo21School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, People’s Republic of China; 2Department of Chemical and Materials Engineering, University of Alberta, Edmonton,...

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Autores principales:	Wang LN, Jin M, Zheng Y, Guan Y, Lu X, Luo JL
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/ff1050a0869e4f2daeebfc51c644cb05
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spelling	oai:doaj.org-article:ff1050a0869e4f2daeebfc51c644cb052021-12-02T02:34:53ZNanotubular surface modification of metallic implants via electrochemical anodization technique1178-2013https://doaj.org/article/ff1050a0869e4f2daeebfc51c644cb052014-09-01T00:00:00Zhttp://www.dovepress.com/nanotubular-surface-modification-of-metallic-implants-via-electrochemi-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013 Lu-Ning Wang,1 Ming Jin,1 Yudong Zheng,1 Yueping Guan,1 Xin Lu,1 Jing-Li Luo21School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, People’s Republic of China; 2Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, CanadaAbstract: Due to increased awareness and interest in the biomedical implant field as a result of an aging population, research in the field of implantable devices has grown rapidly in the last few decades. Among the biomedical implants, metallic implant materials have been widely used to replace disordered bony tissues in orthopedic and orthodontic surgeries. The clinical success of implants is closely related to their early osseointegration (ie, the direct structural and functional connection between living bone and the surface of a load-bearing artificial implant), which relies heavily on the surface condition of the implant. Electrochemical techniques for modifying biomedical implants are relatively simple, cost-effective, and appropriate for implants with complex shapes. Recently, metal oxide nanotubular arrays via electrochemical anodization have become an attractive technique to build up on metallic implants to enhance the biocompatibility and bioactivity. This article will thoroughly review the relevance of electrochemical anodization techniques for the modification of metallic implant surfaces in nanoscale, and cover the electrochemical anodization techniques used in the development of the types of nanotubular/nanoporous modification achievable via electrochemical approaches, which hold tremendous potential for bio-implant applications. In vitro and in vivo studies using metallic oxide nanotubes are also presented, revealing the potential of nanotubes in biomedical applications. Finally, an outlook of future growth of research in metallic oxide nanotubular arrays is provided. This article will therefore provide researchers with an in-depth understanding of electrochemical anodization modification and provide guidance regarding the design and tuning of new materials to achieve a desired performance and reliable biocompatibility.Keywords: nanotubular arrays, anodization, implant, bioactivity, in vitro, in vivoWang LNJin MZheng YGuan YLu XLuo JLDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 4421-4435 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Wang LN Jin M Zheng Y Guan Y Lu X Luo JL Nanotubular surface modification of metallic implants via electrochemical anodization technique
description	Lu-Ning Wang,1 Ming Jin,1 Yudong Zheng,1 Yueping Guan,1 Xin Lu,1 Jing-Li Luo21School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, People’s Republic of China; 2Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, CanadaAbstract: Due to increased awareness and interest in the biomedical implant field as a result of an aging population, research in the field of implantable devices has grown rapidly in the last few decades. Among the biomedical implants, metallic implant materials have been widely used to replace disordered bony tissues in orthopedic and orthodontic surgeries. The clinical success of implants is closely related to their early osseointegration (ie, the direct structural and functional connection between living bone and the surface of a load-bearing artificial implant), which relies heavily on the surface condition of the implant. Electrochemical techniques for modifying biomedical implants are relatively simple, cost-effective, and appropriate for implants with complex shapes. Recently, metal oxide nanotubular arrays via electrochemical anodization have become an attractive technique to build up on metallic implants to enhance the biocompatibility and bioactivity. This article will thoroughly review the relevance of electrochemical anodization techniques for the modification of metallic implant surfaces in nanoscale, and cover the electrochemical anodization techniques used in the development of the types of nanotubular/nanoporous modification achievable via electrochemical approaches, which hold tremendous potential for bio-implant applications. In vitro and in vivo studies using metallic oxide nanotubes are also presented, revealing the potential of nanotubes in biomedical applications. Finally, an outlook of future growth of research in metallic oxide nanotubular arrays is provided. This article will therefore provide researchers with an in-depth understanding of electrochemical anodization modification and provide guidance regarding the design and tuning of new materials to achieve a desired performance and reliable biocompatibility.Keywords: nanotubular arrays, anodization, implant, bioactivity, in vitro, in vivo
format	article
author	Wang LN Jin M Zheng Y Guan Y Lu X Luo JL
author_facet	Wang LN Jin M Zheng Y Guan Y Lu X Luo JL
author_sort	Wang LN
title	Nanotubular surface modification of metallic implants via electrochemical anodization technique
title_short	Nanotubular surface modification of metallic implants via electrochemical anodization technique
title_full	Nanotubular surface modification of metallic implants via electrochemical anodization technique
title_fullStr	Nanotubular surface modification of metallic implants via electrochemical anodization technique
title_full_unstemmed	Nanotubular surface modification of metallic implants via electrochemical anodization technique
title_sort	nanotubular surface modification of metallic implants via electrochemical anodization technique
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/ff1050a0869e4f2daeebfc51c644cb05
work_keys_str_mv	AT wangln nanotubularsurfacemodificationofmetallicimplantsviaelectrochemicalanodizationtechnique AT jinm nanotubularsurfacemodificationofmetallicimplantsviaelectrochemicalanodizationtechnique AT zhengy nanotubularsurfacemodificationofmetallicimplantsviaelectrochemicalanodizationtechnique AT guany nanotubularsurfacemodificationofmetallicimplantsviaelectrochemicalanodizationtechnique AT lux nanotubularsurfacemodificationofmetallicimplantsviaelectrochemicalanodizationtechnique AT luojl nanotubularsurfacemodificationofmetallicimplantsviaelectrochemicalanodizationtechnique
_version_	1718402385789845504

Nanotubular surface modification of metallic implants via electrochemical anodization technique

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