Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease

Non-human primate models of autism spectrum disorder (ASD) are few and not well characterised. Here, the authors describe synaptic function and gene expression changes in a marmoset model of ASD from birth to juvenile, highlighting its similarity to features observed in human ASD.

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Autores principales:	Satoshi Watanabe, Tohru Kurotani, Tomofumi Oga, Jun Noguchi, Risa Isoda, Akiko Nakagami, Kazuhisa Sakai, Keiko Nakagaki, Kayo Sumida, Kohei Hoshino, Koichi Saito, Izuru Miyawaki, Masayuki Sekiguchi, Keiji Wada, Takafumi Minamimoto, Noritaka Ichinohe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ff15042da3814687be3f3c1366d54ae2
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spelling	oai:doaj.org-article:ff15042da3814687be3f3c1366d54ae22021-12-02T15:15:41ZFunctional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease10.1038/s41467-021-25487-62041-1723https://doaj.org/article/ff15042da3814687be3f3c1366d54ae22021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25487-6https://doaj.org/toc/2041-1723Non-human primate models of autism spectrum disorder (ASD) are few and not well characterised. Here, the authors describe synaptic function and gene expression changes in a marmoset model of ASD from birth to juvenile, highlighting its similarity to features observed in human ASD.Satoshi WatanabeTohru KurotaniTomofumi OgaJun NoguchiRisa IsodaAkiko NakagamiKazuhisa SakaiKeiko NakagakiKayo SumidaKohei HoshinoKoichi SaitoIzuru MiyawakiMasayuki SekiguchiKeiji WadaTakafumi MinamimotoNoritaka IchinoheNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Satoshi Watanabe Tohru Kurotani Tomofumi Oga Jun Noguchi Risa Isoda Akiko Nakagami Kazuhisa Sakai Keiko Nakagaki Kayo Sumida Kohei Hoshino Koichi Saito Izuru Miyawaki Masayuki Sekiguchi Keiji Wada Takafumi Minamimoto Noritaka Ichinohe Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease
description	Non-human primate models of autism spectrum disorder (ASD) are few and not well characterised. Here, the authors describe synaptic function and gene expression changes in a marmoset model of ASD from birth to juvenile, highlighting its similarity to features observed in human ASD.
format	article
author	Satoshi Watanabe Tohru Kurotani Tomofumi Oga Jun Noguchi Risa Isoda Akiko Nakagami Kazuhisa Sakai Keiko Nakagaki Kayo Sumida Kohei Hoshino Koichi Saito Izuru Miyawaki Masayuki Sekiguchi Keiji Wada Takafumi Minamimoto Noritaka Ichinohe
author_facet	Satoshi Watanabe Tohru Kurotani Tomofumi Oga Jun Noguchi Risa Isoda Akiko Nakagami Kazuhisa Sakai Keiko Nakagaki Kayo Sumida Kohei Hoshino Koichi Saito Izuru Miyawaki Masayuki Sekiguchi Keiji Wada Takafumi Minamimoto Noritaka Ichinohe
author_sort	Satoshi Watanabe
title	Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease
title_short	Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease
title_full	Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease
title_fullStr	Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease
title_full_unstemmed	Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease
title_sort	functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ff15042da3814687be3f3c1366d54ae2
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Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease

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