Controlling T cells spreading, mechanics and activation by micropatterning

Abstract We designed a strategy, based on a careful examination of the activation capabilities of proteins and antibodies used as substrates for adhering T cells, coupled to protein microstamping to control at the same time the position, shape, spreading, mechanics and activation state of T cells. O...

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Bibliographic Details
Main Authors: Anaïs Sadoun, Martine Biarnes-Pelicot, Laura Ghesquiere-Dierickx, Ambroise Wu, Olivier Théodoly, Laurent Limozin, Yannick Hamon, Pierre-Henri Puech
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/ff1e48ef684a4b078137f5fce273a6b2
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