Placental secretome characterization identifies candidates for pregnancy complications

Napso et al. identify proteins from mouse placental endocrine cells and create a comprehensive secretome map of the placenta. The authors compare this secretome map with human placental datasets from women with pregnancy complications and demonstrate the utility of this method in identifying placent...

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Autores principales:	Tina Napso, Xiaohui Zhao, Marta Ibañez Lligoña, Ionel Sandovici, Richard G. Kay, Amy L. George, Fiona M. Gribble, Frank Reimann, Claire L. Meek, Russell S. Hamilton, Amanda N. Sferruzzi-Perri
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/ff2b898ea1e54b2b8684c6ba582ddc31
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spelling	oai:doaj.org-article:ff2b898ea1e54b2b8684c6ba582ddc312021-12-02T17:34:48ZPlacental secretome characterization identifies candidates for pregnancy complications10.1038/s42003-021-02214-x2399-3642https://doaj.org/article/ff2b898ea1e54b2b8684c6ba582ddc312021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02214-xhttps://doaj.org/toc/2399-3642Napso et al. identify proteins from mouse placental endocrine cells and create a comprehensive secretome map of the placenta. The authors compare this secretome map with human placental datasets from women with pregnancy complications and demonstrate the utility of this method in identifying placental protein candidates and transcription factors that could be useful as biomarkers for pregnancy complications.Tina NapsoXiaohui ZhaoMarta Ibañez LligoñaIonel SandoviciRichard G. KayAmy L. GeorgeFiona M. GribbleFrank ReimannClaire L. MeekRussell S. HamiltonAmanda N. Sferruzzi-PerriNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Tina Napso Xiaohui Zhao Marta Ibañez Lligoña Ionel Sandovici Richard G. Kay Amy L. George Fiona M. Gribble Frank Reimann Claire L. Meek Russell S. Hamilton Amanda N. Sferruzzi-Perri Placental secretome characterization identifies candidates for pregnancy complications
description	Napso et al. identify proteins from mouse placental endocrine cells and create a comprehensive secretome map of the placenta. The authors compare this secretome map with human placental datasets from women with pregnancy complications and demonstrate the utility of this method in identifying placental protein candidates and transcription factors that could be useful as biomarkers for pregnancy complications.
format	article
author	Tina Napso Xiaohui Zhao Marta Ibañez Lligoña Ionel Sandovici Richard G. Kay Amy L. George Fiona M. Gribble Frank Reimann Claire L. Meek Russell S. Hamilton Amanda N. Sferruzzi-Perri
author_facet	Tina Napso Xiaohui Zhao Marta Ibañez Lligoña Ionel Sandovici Richard G. Kay Amy L. George Fiona M. Gribble Frank Reimann Claire L. Meek Russell S. Hamilton Amanda N. Sferruzzi-Perri
author_sort	Tina Napso
title	Placental secretome characterization identifies candidates for pregnancy complications
title_short	Placental secretome characterization identifies candidates for pregnancy complications
title_full	Placental secretome characterization identifies candidates for pregnancy complications
title_fullStr	Placental secretome characterization identifies candidates for pregnancy complications
title_full_unstemmed	Placental secretome characterization identifies candidates for pregnancy complications
title_sort	placental secretome characterization identifies candidates for pregnancy complications
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ff2b898ea1e54b2b8684c6ba582ddc31
work_keys_str_mv	AT tinanapso placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT xiaohuizhao placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT martaibanezlligona placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT ionelsandovici placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT richardgkay placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT amylgeorge placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT fionamgribble placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT frankreimann placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT clairelmeek placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT russellshamilton placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications AT amandansferruzziperri placentalsecretomecharacterizationidentifiescandidatesforpregnancycomplications
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Placental secretome characterization identifies candidates for pregnancy complications

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