Trauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress

The nervous system utilizes adaptive strategies to mitigate trauma-induced neurodegeneration. Here, the authors report that a MAPK phosphatase VHP-1 is induced by trauma and regulates transcriptional responses to mechanical stress in a C. elegans model.

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Autores principales: Nathan Egge, Sonja L. B. Arneaud, Rene Solano Fonseca, Kielen R. Zuurbier, Jacob McClendon, Peter M. Douglas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ff44cb20fe82453182d0e975c52b4f95
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spelling oai:doaj.org-article:ff44cb20fe82453182d0e975c52b4f952021-12-02T13:14:53ZTrauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress10.1038/s41467-021-21611-82041-1723https://doaj.org/article/ff44cb20fe82453182d0e975c52b4f952021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21611-8https://doaj.org/toc/2041-1723The nervous system utilizes adaptive strategies to mitigate trauma-induced neurodegeneration. Here, the authors report that a MAPK phosphatase VHP-1 is induced by trauma and regulates transcriptional responses to mechanical stress in a C. elegans model.Nathan EggeSonja L. B. ArneaudRene Solano FonsecaKielen R. ZuurbierJacob McClendonPeter M. DouglasNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nathan Egge
Sonja L. B. Arneaud
Rene Solano Fonseca
Kielen R. Zuurbier
Jacob McClendon
Peter M. Douglas
Trauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress
description The nervous system utilizes adaptive strategies to mitigate trauma-induced neurodegeneration. Here, the authors report that a MAPK phosphatase VHP-1 is induced by trauma and regulates transcriptional responses to mechanical stress in a C. elegans model.
format article
author Nathan Egge
Sonja L. B. Arneaud
Rene Solano Fonseca
Kielen R. Zuurbier
Jacob McClendon
Peter M. Douglas
author_facet Nathan Egge
Sonja L. B. Arneaud
Rene Solano Fonseca
Kielen R. Zuurbier
Jacob McClendon
Peter M. Douglas
author_sort Nathan Egge
title Trauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress
title_short Trauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress
title_full Trauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress
title_fullStr Trauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress
title_full_unstemmed Trauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress
title_sort trauma-induced regulation of vhp-1 modulates the cellular response to mechanical stress
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ff44cb20fe82453182d0e975c52b4f95
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AT kielenrzuurbier traumainducedregulationofvhp1modulatesthecellularresponsetomechanicalstress
AT jacobmcclendon traumainducedregulationofvhp1modulatesthecellularresponsetomechanicalstress
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