Asc Modulates the Function of NLRC4 in Response to Infection of Macrophages by <named-content content-type="genus-species">Legionella pneumophila</named-content>

Asc Modulates the Function of NLRC4 in Response to Infection of Macrophages by <named-content content-type="genus-species">Legionella pneumophila</named-content>

ABSTRACT Nucleotide-binding domain, leucine-rich repeat containing proteins (NLRs) activate caspase-1 in response to a variety of bacterium-derived signals in macrophages. NLR-mediated activation of caspase-1 by Legionella pneumophila occurs through both an NLRC4/NAIP5-dependent pathway and a pathwa...

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Autores principales: Christopher L. Case, Craig R. Roy
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/ff512a27e47e44f199f816dadbb11dda
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