Asc Modulates the Function of NLRC4 in Response to Infection of Macrophages by <named-content content-type="genus-species">Legionella pneumophila</named-content>
ABSTRACT Nucleotide-binding domain, leucine-rich repeat containing proteins (NLRs) activate caspase-1 in response to a variety of bacterium-derived signals in macrophages. NLR-mediated activation of caspase-1 by Legionella pneumophila occurs through both an NLRC4/NAIP5-dependent pathway and a pathwa...
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| Main Authors: | , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2011
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| Subjects: | |
| Online Access: | https://doaj.org/article/ff512a27e47e44f199f816dadbb11dda |
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