MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair
MAD2L2 — a member of the shieldin complex — is known to play important roles in DNA repair. Here the authors demonstrate how MAD2L2 dimerization mediated through SHLD2 participates in shieldin assembly and function.
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Nature Portfolio
2021
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oai:doaj.org-article:ff52d6b334fd4c1a8c8a1c74813d0adb2021-12-02T17:25:34ZMAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair10.1038/s41467-021-25724-y2041-1723https://doaj.org/article/ff52d6b334fd4c1a8c8a1c74813d0adb2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25724-yhttps://doaj.org/toc/2041-1723MAD2L2 — a member of the shieldin complex — is known to play important roles in DNA repair. Here the authors demonstrate how MAD2L2 dimerization mediated through SHLD2 participates in shieldin assembly and function.Inge de KrijgerBastian FöhrSantiago Hernández PérezEstelle VincendeauJudit SerratAlexander Marc ThouinVivek SusvirkarChloé LescaleInés PaniaguaLiesbeth HoekmanSimranjeet KaurMaarten AltelaarLudovic DerianoAlex C. FaesenJacqueline J. L. JacobsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Inge de Krijger Bastian Föhr Santiago Hernández Pérez Estelle Vincendeau Judit Serrat Alexander Marc Thouin Vivek Susvirkar Chloé Lescale Inés Paniagua Liesbeth Hoekman Simranjeet Kaur Maarten Altelaar Ludovic Deriano Alex C. Faesen Jacqueline J. L. Jacobs MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair |
| description |
MAD2L2 — a member of the shieldin complex — is known to play important roles in DNA repair. Here the authors demonstrate how MAD2L2 dimerization mediated through SHLD2 participates in shieldin assembly and function. |
| format |
article |
| author |
Inge de Krijger Bastian Föhr Santiago Hernández Pérez Estelle Vincendeau Judit Serrat Alexander Marc Thouin Vivek Susvirkar Chloé Lescale Inés Paniagua Liesbeth Hoekman Simranjeet Kaur Maarten Altelaar Ludovic Deriano Alex C. Faesen Jacqueline J. L. Jacobs |
| author_facet |
Inge de Krijger Bastian Föhr Santiago Hernández Pérez Estelle Vincendeau Judit Serrat Alexander Marc Thouin Vivek Susvirkar Chloé Lescale Inés Paniagua Liesbeth Hoekman Simranjeet Kaur Maarten Altelaar Ludovic Deriano Alex C. Faesen Jacqueline J. L. Jacobs |
| author_sort |
Inge de Krijger |
| title |
MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair |
| title_short |
MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair |
| title_full |
MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair |
| title_fullStr |
MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair |
| title_full_unstemmed |
MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair |
| title_sort |
mad2l2 dimerization and trip13 control shieldin activity in dna repair |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/ff52d6b334fd4c1a8c8a1c74813d0adb |
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