ClusterMap for multi-scale clustering analysis of spatial gene expression

In situ transcriptomics maps RNA expression patterns across intact tissues taking our understanding of gene expression to a new level. Here, the authors present a computational method that uncovers gene expression, cell niche, and tissue region patterns from 2D and 3D spatial transcriptomics.

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Autores principales: Yichun He, Xin Tang, Jiahao Huang, Jingyi Ren, Haowen Zhou, Kevin Chen, Albert Liu, Hailing Shi, Zuwan Lin, Qiang Li, Abhishek Aditham, Johain Ounadjela, Emanuelle I. Grody, Jian Shu, Jia Liu, Xiao Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ff58b316e7154332a514271fdae78380
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spelling oai:doaj.org-article:ff58b316e7154332a514271fdae783802021-12-02T18:07:53ZClusterMap for multi-scale clustering analysis of spatial gene expression10.1038/s41467-021-26044-x2041-1723https://doaj.org/article/ff58b316e7154332a514271fdae783802021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26044-xhttps://doaj.org/toc/2041-1723In situ transcriptomics maps RNA expression patterns across intact tissues taking our understanding of gene expression to a new level. Here, the authors present a computational method that uncovers gene expression, cell niche, and tissue region patterns from 2D and 3D spatial transcriptomics.Yichun HeXin TangJiahao HuangJingyi RenHaowen ZhouKevin ChenAlbert LiuHailing ShiZuwan LinQiang LiAbhishek AdithamJohain OunadjelaEmanuelle I. GrodyJian ShuJia LiuXiao WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yichun He
Xin Tang
Jiahao Huang
Jingyi Ren
Haowen Zhou
Kevin Chen
Albert Liu
Hailing Shi
Zuwan Lin
Qiang Li
Abhishek Aditham
Johain Ounadjela
Emanuelle I. Grody
Jian Shu
Jia Liu
Xiao Wang
ClusterMap for multi-scale clustering analysis of spatial gene expression
description In situ transcriptomics maps RNA expression patterns across intact tissues taking our understanding of gene expression to a new level. Here, the authors present a computational method that uncovers gene expression, cell niche, and tissue region patterns from 2D and 3D spatial transcriptomics.
format article
author Yichun He
Xin Tang
Jiahao Huang
Jingyi Ren
Haowen Zhou
Kevin Chen
Albert Liu
Hailing Shi
Zuwan Lin
Qiang Li
Abhishek Aditham
Johain Ounadjela
Emanuelle I. Grody
Jian Shu
Jia Liu
Xiao Wang
author_facet Yichun He
Xin Tang
Jiahao Huang
Jingyi Ren
Haowen Zhou
Kevin Chen
Albert Liu
Hailing Shi
Zuwan Lin
Qiang Li
Abhishek Aditham
Johain Ounadjela
Emanuelle I. Grody
Jian Shu
Jia Liu
Xiao Wang
author_sort Yichun He
title ClusterMap for multi-scale clustering analysis of spatial gene expression
title_short ClusterMap for multi-scale clustering analysis of spatial gene expression
title_full ClusterMap for multi-scale clustering analysis of spatial gene expression
title_fullStr ClusterMap for multi-scale clustering analysis of spatial gene expression
title_full_unstemmed ClusterMap for multi-scale clustering analysis of spatial gene expression
title_sort clustermap for multi-scale clustering analysis of spatial gene expression
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ff58b316e7154332a514271fdae78380
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