Impact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study

Abstract This study investigated the impact of bronchiectasis on patients admitted to the intensive care unit (ICU) at a hospital in Korea. Patients with bronchiectasis were diagnosed using results of chest computed tomography performed before ICU admission. The severity of bronchiectasis was based...

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Autores principales:	Youngmok Park, Seung Hyun Yong, Ah Young Leem, Song Yee Kim, Sang Hoon Lee, Kyungsoo Chung, Eun Young Kim, Ji Ye Jung, Young Ae Kang, Moo Suk Park, Young Sam Kim, Su Hwan Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ff70cbf42dd448f996be0ceb0a3b3e58
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spelling	oai:doaj.org-article:ff70cbf42dd448f996be0ceb0a3b3e582021-12-02T18:49:17ZImpact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study10.1038/s41598-021-95366-z2045-2322https://doaj.org/article/ff70cbf42dd448f996be0ceb0a3b3e582021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95366-zhttps://doaj.org/toc/2045-2322Abstract This study investigated the impact of bronchiectasis on patients admitted to the intensive care unit (ICU) at a hospital in Korea. Patients with bronchiectasis were diagnosed using results of chest computed tomography performed before ICU admission. The severity of bronchiectasis was based on the number of affected lobes, and patients with ≥ 3 bronchiectatic lobes were classified into the severe bronchiectasis group. Overall, 823 patients were enrolled. The mean age was 66.0 ± 13.9 years, and 63.4% were men. Bronchiectasis and severe bronchiectasis were present in 148 (18.0%) and 108 (13.1%) patients, respectively. The increase in the number of bronchiectatic lobes was related to the rise in ICU mortality (P for trend = 0.012) and in-hospital mortality (P for trend = 0.004). Patients with severe bronchiectasis had higher odds for 28-day mortality [odds ratio (OR) 1.122, 95% confidence interval (CI) 1.024–1.230], ICU mortality (OR 1.119, 95% CI 1.023–1.223), and in-hospital mortality (OR 1.208, 95% CI 1.092–1.337). The severe bronchiectasis group showed lower overall survival (log-rank P < 0.001), and the adjusted hazard ratio was 1.535 (95% CI 1.178–2.001). Severe bronchiectasis had a negative impact on all-cause mortality during ICU and hospital stays, resulting in a lower survival rate.Youngmok ParkSeung Hyun YongAh Young LeemSong Yee KimSang Hoon LeeKyungsoo ChungEun Young KimJi Ye JungYoung Ae KangMoo Suk ParkYoung Sam KimSu Hwan LeeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Youngmok Park Seung Hyun Yong Ah Young Leem Song Yee Kim Sang Hoon Lee Kyungsoo Chung Eun Young Kim Ji Ye Jung Young Ae Kang Moo Suk Park Young Sam Kim Su Hwan Lee Impact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study
description	Abstract This study investigated the impact of bronchiectasis on patients admitted to the intensive care unit (ICU) at a hospital in Korea. Patients with bronchiectasis were diagnosed using results of chest computed tomography performed before ICU admission. The severity of bronchiectasis was based on the number of affected lobes, and patients with ≥ 3 bronchiectatic lobes were classified into the severe bronchiectasis group. Overall, 823 patients were enrolled. The mean age was 66.0 ± 13.9 years, and 63.4% were men. Bronchiectasis and severe bronchiectasis were present in 148 (18.0%) and 108 (13.1%) patients, respectively. The increase in the number of bronchiectatic lobes was related to the rise in ICU mortality (P for trend = 0.012) and in-hospital mortality (P for trend = 0.004). Patients with severe bronchiectasis had higher odds for 28-day mortality [odds ratio (OR) 1.122, 95% confidence interval (CI) 1.024–1.230], ICU mortality (OR 1.119, 95% CI 1.023–1.223), and in-hospital mortality (OR 1.208, 95% CI 1.092–1.337). The severe bronchiectasis group showed lower overall survival (log-rank P < 0.001), and the adjusted hazard ratio was 1.535 (95% CI 1.178–2.001). Severe bronchiectasis had a negative impact on all-cause mortality during ICU and hospital stays, resulting in a lower survival rate.
format	article
author	Youngmok Park Seung Hyun Yong Ah Young Leem Song Yee Kim Sang Hoon Lee Kyungsoo Chung Eun Young Kim Ji Ye Jung Young Ae Kang Moo Suk Park Young Sam Kim Su Hwan Lee
author_facet	Youngmok Park Seung Hyun Yong Ah Young Leem Song Yee Kim Sang Hoon Lee Kyungsoo Chung Eun Young Kim Ji Ye Jung Young Ae Kang Moo Suk Park Young Sam Kim Su Hwan Lee
author_sort	Youngmok Park
title	Impact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study
title_short	Impact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study
title_full	Impact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study
title_fullStr	Impact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study
title_full_unstemmed	Impact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study
title_sort	impact of non-cystic fibrosis bronchiectasis on critically ill patients in korea: a retrospective observational study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ff70cbf42dd448f996be0ceb0a3b3e58
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Impact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study

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