MicroRNA-146a and Ets-1 gene polymorphisms are associated with pediatric uveitis.

MicroRNA-146a and Ets-1 gene polymorphisms are associated with pediatric uveitis.

<h4>Background</h4>MicroRNA-146a (miR-146a) was a key negative regulator of autoimmunity. V-Ets oncogene homolog 1 (Ets-1) was demonstrated to bind to the miR-146a promoter region and markedly affects miR-146a promoter activity. This study aimed to investigate the association of miR-146a...

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Autores principales: Lin Wei, Qingyun Zhou, Shengping Hou, Lin Bai, Yunjia Liu, Jian Qi, Qin Xiang, Yan Zhou, Aize Kijlstra, Peizeng Yang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ff76c947853444d79bfc29b76da7fcca
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