Simultaneous construction of axial and planar chirality by gold/TY-Phos-catalyzed asymmetric hydroarylation

The simultaneous construction of two different types of chiralities is challenging. Here, the authors report a cationic gold-catalyzed asymmetric hydroarylation of ortho-alkynylaryl ferrocene derivatives, which enabled the simultaneous construction of axial and planar chirality.

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Auteurs principaux: Pei-Chao Zhang, Yin-Lin Li, Jiafeng He, Hai-Hong Wu, Zhiming Li, Junliang Zhang
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/ff7b6d4792e14b2eabcb2f9f7655730f
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