Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling

Most currently available statistical tools for the analysis of ATAC-seq data were repurposed from tools developed for other functional genomics data (e.g. ChIP-seq). Here, Gabitto et al develop ChromA, a Bayesian statistical approach for the analysis of both bulk and single-cell ATAC-seq data.

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Autores principales:	Mariano I. Gabitto, Anders Rasmussen, Orly Wapinski, Kathryn Allaway, Nicholas Carriero, Gordon J. Fishell, Richard Bonneau
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ff875af4ced749c59fcbbc72569eff52
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spelling	oai:doaj.org-article:ff875af4ced749c59fcbbc72569eff522021-12-02T14:40:53ZCharacterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling10.1038/s41467-020-14497-52041-1723https://doaj.org/article/ff875af4ced749c59fcbbc72569eff522020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14497-5https://doaj.org/toc/2041-1723Most currently available statistical tools for the analysis of ATAC-seq data were repurposed from tools developed for other functional genomics data (e.g. ChIP-seq). Here, Gabitto et al develop ChromA, a Bayesian statistical approach for the analysis of both bulk and single-cell ATAC-seq data.Mariano I. GabittoAnders RasmussenOrly WapinskiKathryn AllawayNicholas CarrieroGordon J. FishellRichard BonneauNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mariano I. Gabitto Anders Rasmussen Orly Wapinski Kathryn Allaway Nicholas Carriero Gordon J. Fishell Richard Bonneau Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling
description	Most currently available statistical tools for the analysis of ATAC-seq data were repurposed from tools developed for other functional genomics data (e.g. ChIP-seq). Here, Gabitto et al develop ChromA, a Bayesian statistical approach for the analysis of both bulk and single-cell ATAC-seq data.
format	article
author	Mariano I. Gabitto Anders Rasmussen Orly Wapinski Kathryn Allaway Nicholas Carriero Gordon J. Fishell Richard Bonneau
author_facet	Mariano I. Gabitto Anders Rasmussen Orly Wapinski Kathryn Allaway Nicholas Carriero Gordon J. Fishell Richard Bonneau
author_sort	Mariano I. Gabitto
title	Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling
title_short	Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling
title_full	Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling
title_fullStr	Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling
title_full_unstemmed	Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling
title_sort	characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/ff875af4ced749c59fcbbc72569eff52
work_keys_str_mv	AT marianoigabitto characterizingchromatinlandscapefromaggregateandsinglecellgenomicassaysusingflexibledurationmodeling AT andersrasmussen characterizingchromatinlandscapefromaggregateandsinglecellgenomicassaysusingflexibledurationmodeling AT orlywapinski characterizingchromatinlandscapefromaggregateandsinglecellgenomicassaysusingflexibledurationmodeling AT kathrynallaway characterizingchromatinlandscapefromaggregateandsinglecellgenomicassaysusingflexibledurationmodeling AT nicholascarriero characterizingchromatinlandscapefromaggregateandsinglecellgenomicassaysusingflexibledurationmodeling AT gordonjfishell characterizingchromatinlandscapefromaggregateandsinglecellgenomicassaysusingflexibledurationmodeling AT richardbonneau characterizingchromatinlandscapefromaggregateandsinglecellgenomicassaysusingflexibledurationmodeling
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Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling

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