Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disorder characterised by asthma, eosinophilia and vasculitis. Here, the authors describe a genome-wide association study of EGPA that reveals clinical and genetic differences between subgroups stratified by autoantibody sta...

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Autores principales:	Paul A Lyons, James E Peters, Federico Alberici, James Liley, Richard M. R. Coulson, William Astle, Chiara Baldini, Francesco Bonatti, Maria C Cid, Heather Elding, Giacomo Emmi, Jörg Epplen, Loïc Guillevin, David R. W. Jayne, Tao Jiang, Iva Gunnarsson, Peter Lamprecht, Stephen Leslie, Mark A. Little, Davide Martorana, Frank Moosig, Thomas Neumann, Sophie Ohlsson, Stefanie Quickert, Giuseppe A. Ramirez, Barbara Rewerska, Georg Schett, Renato A. Sinico, Wojciech Szczeklik, Vladimir Tesar, Damjan Vukcevic, The European Vasculitis Genetics Consortium, Benjamin Terrier, Richard A Watts, Augusto Vaglio, Julia U Holle, Chris Wallace, Kenneth G. C. Smith
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ff891c79b773423a95539793d707bc9a
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spelling	oai:doaj.org-article:ff891c79b773423a95539793d707bc9a2021-12-02T14:39:03ZGenome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status10.1038/s41467-019-12515-92041-1723https://doaj.org/article/ff891c79b773423a95539793d707bc9a2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12515-9https://doaj.org/toc/2041-1723Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disorder characterised by asthma, eosinophilia and vasculitis. Here, the authors describe a genome-wide association study of EGPA that reveals clinical and genetic differences between subgroups stratified by autoantibody status (ANCA).Paul A LyonsJames E PetersFederico AlbericiJames LileyRichard M. R. CoulsonWilliam AstleChiara BaldiniFrancesco BonattiMaria C CidHeather EldingGiacomo EmmiJörg EpplenLoïc GuillevinDavid R. W. JayneTao JiangIva GunnarssonPeter LamprechtStephen LeslieMark A. LittleDavide MartoranaFrank MoosigThomas NeumannSophie OhlssonStefanie QuickertGiuseppe A. RamirezBarbara RewerskaGeorg SchettRenato A. SinicoWojciech SzczeklikVladimir TesarDamjan VukcevicThe European Vasculitis Genetics ConsortiumBenjamin TerrierRichard A WattsAugusto VaglioJulia U HolleChris WallaceKenneth G. C. SmithNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Paul A Lyons James E Peters Federico Alberici James Liley Richard M. R. Coulson William Astle Chiara Baldini Francesco Bonatti Maria C Cid Heather Elding Giacomo Emmi Jörg Epplen Loïc Guillevin David R. W. Jayne Tao Jiang Iva Gunnarsson Peter Lamprecht Stephen Leslie Mark A. Little Davide Martorana Frank Moosig Thomas Neumann Sophie Ohlsson Stefanie Quickert Giuseppe A. Ramirez Barbara Rewerska Georg Schett Renato A. Sinico Wojciech Szczeklik Vladimir Tesar Damjan Vukcevic The European Vasculitis Genetics Consortium Benjamin Terrier Richard A Watts Augusto Vaglio Julia U Holle Chris Wallace Kenneth G. C. Smith Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status
description	Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disorder characterised by asthma, eosinophilia and vasculitis. Here, the authors describe a genome-wide association study of EGPA that reveals clinical and genetic differences between subgroups stratified by autoantibody status (ANCA).
format	article
author	Paul A Lyons James E Peters Federico Alberici James Liley Richard M. R. Coulson William Astle Chiara Baldini Francesco Bonatti Maria C Cid Heather Elding Giacomo Emmi Jörg Epplen Loïc Guillevin David R. W. Jayne Tao Jiang Iva Gunnarsson Peter Lamprecht Stephen Leslie Mark A. Little Davide Martorana Frank Moosig Thomas Neumann Sophie Ohlsson Stefanie Quickert Giuseppe A. Ramirez Barbara Rewerska Georg Schett Renato A. Sinico Wojciech Szczeklik Vladimir Tesar Damjan Vukcevic The European Vasculitis Genetics Consortium Benjamin Terrier Richard A Watts Augusto Vaglio Julia U Holle Chris Wallace Kenneth G. C. Smith
author_facet	Paul A Lyons James E Peters Federico Alberici James Liley Richard M. R. Coulson William Astle Chiara Baldini Francesco Bonatti Maria C Cid Heather Elding Giacomo Emmi Jörg Epplen Loïc Guillevin David R. W. Jayne Tao Jiang Iva Gunnarsson Peter Lamprecht Stephen Leslie Mark A. Little Davide Martorana Frank Moosig Thomas Neumann Sophie Ohlsson Stefanie Quickert Giuseppe A. Ramirez Barbara Rewerska Georg Schett Renato A. Sinico Wojciech Szczeklik Vladimir Tesar Damjan Vukcevic The European Vasculitis Genetics Consortium Benjamin Terrier Richard A Watts Augusto Vaglio Julia U Holle Chris Wallace Kenneth G. C. Smith
author_sort	Paul A Lyons
title	Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status
title_short	Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status
title_full	Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status
title_fullStr	Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status
title_full_unstemmed	Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status
title_sort	genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by anca status
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ff891c79b773423a95539793d707bc9a
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Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

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