Comprehensive Functional Analysis of N-Linked Glycans on Ebola Virus GP1
ABSTRACT Ebola virus (EBOV) entry requires the virion surface-associated glycoprotein (GP) that is composed of a trimer of heterodimers (GP1/GP2). The GP1 subunit contains two heavily glycosylated domains, the glycan cap and the mucin-like domain (MLD). The glycan cap contains only N-linked glycans,...
Saved in:
Main Authors: | Nicholas J. Lennemann, Bethany A. Rhein, Esther Ndungo, Kartik Chandran, Xiangguo Qiu, Wendy Maury |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2014
|
Subjects: | |
Online Access: | https://doaj.org/article/ff90187a2eeb499f8e03f3e5653eea9f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies
by: Zachary A. Bornholdt, et al.
Published: (2016) -
Zoonotic risk factors associated with seroprevalence of Ebola virus GP antibodies in the absence of diagnosed Ebola virus disease in the Democratic Republic of Congo.
by: Anna Bratcher, et al.
Published: (2021) -
Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway
by: Jennifer S. Spence, et al.
Published: (2016) -
A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles
by: Esther Ndungo, et al.
Published: (2016) -
Direct Intracellular Visualization of Ebola Virus-Receptor Interaction by
<i>In Situ</i>
Proximity Ligation
by: Eva Mittler, et al.
Published: (2021)