Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis

QR Code

Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis

Helicobacter pylori FabX, a dehydrogenase/isomerase flavoprotein, is required for unsaturated fatty acid synthesis. Here, the authors characterize FabX substrate recognition and catalytic mechanism, and reveal that it contains an atypical [4Fe-4S] cluster, which is essential and participates in the...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Jiashen Zhou, Lin Zhang, Liping Zeng, Lu Yu, Yuanyuan Duan, Siqi Shen, Jingyan Hu, Pan Zhang, Wenyan Song, Xiaoxue Ruan, Jing Jiang, Yinan Zhang, Lu Zhou, Jia Jia, Xudong Hang, Changlin Tian, Houwen Lin, Hong-Zhuan Chen, John E. Cronan, Hongkai Bi, Liang Zhang
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/ff98c86182784a2baf66ddf02f8bcbf9
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Cobalt-catalyzed highly enantioselective hydrogenation of α,β-unsaturated carboxylic acids
par: Xiaoyong Du, et autres
Publié: (2020)

DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously
par: Roland Beckmann, et autres
Publié: (2021)

Investigation on Numerical Simulation of Chloride Transport in Unsaturated Concrete
par: Qingzhang Zhang, et autres
Publié: (2021)

Two novel aliphatic unsaturated alcohols isolated from a pathogenic fungus Fusarium proliferatum
par: Wanying Lu, et autres
Publié: (2021)

VGLL4 targets a TCF4–TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer
par: Shi Jiao, et autres
Publié: (2017)

Influence of Clay Fraction and Mineral Composition on Unsaturated Characteristics of Cohesive Foundation Soil in Airports
par: Jun Feng, et autres
Publié: (2021)

Online photochemical derivatization enables comprehensive mass spectrometric analysis of unsaturated phospholipid isomers
par: Wenpeng Zhang, et autres
Publié: (2019)

AN ECO-FRIENDLY ONE-POT SYNTHESIS OF 4,4'-(ARYLMETHYLENE)BIS(1H-PYRAZOL-5-OLS) USING [Et3NH][HSO4] AS A RECYCLABLE CATALYST
par: ZHOU,ZHONGQIANG, et autres
Publié: (2015)

Role of GATA binding protein 4 (GATA4) in the regulation of tooth development via GNAI3
par: Shuyu Guo, et autres
Publié: (2017)

Cyclin-Dependent Kinase 4 is expected to be a therapeutic target for hepatocellular carcinoma metastasis using integrated bioinformatic analysis
par: Jia-Ning Zhang, et autres
Publié: (2021)

Novel BMP4 Truncations Resulted in Opposite Ocular Anomalies: Pathologic Myopia Rather Than Microphthalmia
par: Yi Jiang, et autres
Publié: (2021)

Computational exploration of copper catalyzed vinylogous aerobic oxidation of unsaturated compounds
par: Ting Wang, et autres
Publié: (2021)

The Functional Assessment of Balance in Concussion (FAB-C) Battery
par: Thaer Manaseer, et autres
Publié: (2021)

Green financing for global energy sustainability: prospecting transformational adaptation beyond Industry 4.0
par: Artie W. Ng, et autres
Publié: (2021)

Publisher Correction: Online photochemical derivatization enables comprehensive mass spectrometric analysis of unsaturated phospholipid isomers
par: Wenpeng Zhang, et autres
Publié: (2019)

Cytochrome P450 3A1 mediates 2,2',4,4'-tetrabromodiphenyl ether-induced reduction of spermatogenesis in adult rats.
par: Zhan Zhang, et autres
Publié: (2013)

Regioselective radical α-borylation of α,β-unsaturated carbonyl compounds for direct synthesis of α-borylcarbonyl molecules
par: Shi-Chao Ren, et autres
Publié: (2019)

Cranial morphology of Deudorix isocrates (Fab.) (Lepidoptera: Lycaenidae) larvae
par: Ravindrakumar D. Patil, et autres
Publié: (2021)

Familial Translocation t(2;4) (q37.3;p16.3), Resulting in a Partial Trisomy of 2q (or 4p) and a Partial Monosomy of 4p (or 2q), Causes Dysplasia
par: Jian Wang, et autres
Publié: (2021)

Trastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo
par: Duan D, et autres
Publié: (2018)

Inactivation of Transcriptional Regulator FabT Influences Colony Phase Variation of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content>
par: Jinghui Zhang, et autres
Publié: (2021)

Genetic segregation analysis of unsaturated fatty acids content in the filial generations of high-linolenic-acid rapeseed (Brassica napus)
par: Xiaohan Zhang, et autres
Publié: (2021)

Expression characteristic of 4Ig B7-H3 and 2Ig B7-H3 in acute myeloid leukemia
par: Wei Zhang, et autres
Publié: (2021)

Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4
par: Ning Lu, et autres
Publié: (2018)

Improved YOLOv4-tiny network for real-time electronic component detection
par: Ce Guo, et autres
Publié: (2021)

Unsaturated fatty acid salts remove biofilms on dentures
par: Teruyuki Hara, et autres
Publié: (2021)

Bearing Capacity Behavior of Skirted Foundations on Unsaturated Soils
par: Mohammed Muthana S., et autres
Publié: (2021)

Photobiocatalytic synthesis of chiral secondary fatty alcohols from renewable unsaturated fatty acids
par: Wuyuan Zhang, et autres
Publié: (2020)

EFFECT OF NITROGEN FERTILIZER AND MAIZE STRAW INCORPORATION ON NH4+15N AND N0(3) -15N ACCUMULATION IN BLACK SOIL OF NORTHEAST CHINA AMONG THREE CONSECUTIVE CROPPING CYCLES
par: Lu,Caiyan, et autres
Publié: (2010)

Comparison of anti-EGFR-Fab’ conjugated immunoliposomes modified with two different conjugation linkers for siRNA delivery in SMMC-7721 cells
par: Deng L, et autres
Publié: (2013)

Roll-to-roll manufacturing toward lab-to-fab-translation of perovskite solar cells
par: Tae-Youl Yang, et autres
Publié: (2021)

Comprehensive Analysis of LPCATs Highlights the Prognostic and Immunological Values of LPCAT1/4 in Hepatocellular Carcinoma
par: Lin T, et autres
Publié: (2021)

2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione isolated from Averrhoa carambola L. root ameliorates diabetic nephropathy by inhibiting the TLR4/MyD88/NF-κB pathway
par: Lu S, et autres
Publié: (2019)

2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione Isolated from Averrhoa carambola L. Root Ameliorates Diabetic Nephropathy by Inhibiting the TLR4/MyD88/NF-κB Pathway [Corrigendum]
par: Lu S, et autres
Publié: (2020)

The Two Functional Enoyl-Acyl Carrier Protein Reductases of <named-content content-type="genus-species">Enterococcus faecalis</named-content> Do Not Mediate Triclosan Resistance
par: Lei Zhu, et autres
Publié: (2013)

Unreconciled effects of salinity on draining and wetting functions in unsaturated soils
par: David P. Huber, et autres
Publié: (2021)

SYNTHESIS OF NOVEL UNSATURATED ORGANOTELLURIUM COMPOUNDS WITH POTENTIAL BIOLOGICAL ACTIVITY
par: M. V. Musalova, et autres
Publié: (2012)

Understanding nitrogen transport in the unsaturated zone with fluctuations in groundwater depth
par: Jianmin Bian, et autres
Publié: (2021)

Room-Temperature Topological Phase Transition in Quasi-One-Dimensional Material Bi_{4}I_{4}
par: Jianwei Huang, et autres
Publié: (2021)

D-4F, an apolipoprotein A-I mimetic, suppresses IL-4 induced macrophage alternative activation and pro-fibrotic TGF-β1 expression
par: Xuejiao Song, et autres
Publié: (2019)