Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital

Abstract Introduction Neuromuscular diseases include a large group of heterogeneous and rare pathologies that affect different components of the motor unit. It is essential to optimize resources to know the prevalence of comorbidities in the most frequent groups to establish an early multidisciplina...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	J. A. Gascón-Navarro, M. J. De La Torre-Aguilar, J. A. Fernández-Ramos, J. Torres-Borrego, J. L. Pérez-Navero
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Pediatrics RJ1-570
Acceso en línea:	https://doaj.org/article/ff9969669f494452afbd90dba146223f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ff9969669f494452afbd90dba146223f
record_format	dspace
spelling	oai:doaj.org-article:ff9969669f494452afbd90dba146223f2021-11-21T12:42:25ZExperience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital10.1186/s13052-021-01176-41824-7288https://doaj.org/article/ff9969669f494452afbd90dba146223f2021-11-01T00:00:00Zhttps://doi.org/10.1186/s13052-021-01176-4https://doaj.org/toc/1824-7288Abstract Introduction Neuromuscular diseases include a large group of heterogeneous and rare pathologies that affect different components of the motor unit. It is essential to optimize resources to know the prevalence of comorbidities in the most frequent groups to establish an early multidisciplinary approach in a specialized setting. Patients and methods Retrospective descriptive study of pediatric and adolescent patients with neuromuscular diseases (NMDs). The Inclusion criteria were NMDs patients with motor neuron involvement divided into three groups, depending on the affected component of the motor unit. Group I: involvement of the motor neuron; Group II: peripheral neuropathies; Group III: myopathies. Demographic variables, association with comorbidities, need for respiratory support, and rehabilitative treatment were collected in each group. Results Ninety-six patients who met the inclusion criteria were studied. In group I, when compared to the other two groups, a higher incidence of scoliosis (68.3%, p = 0.011), deformity of the rib cage (31.3%, p = 0.0001), chronic respiratory insufficiency (62.5%, p = 0.001) and bronchial aspiration (12.5%, p = 0.03) was detected. In this group, 50%of the patients required non-invasive mechanical ventilation (p = 0.0001). The in-hospital requirement for respiratory physiotherapy was higher in group I (75%, p = 0.001). We observed a higher incidence of scoliosis in Group III compared to Group II. Conclusions Neuromuscular diseases with motor neuron involvement present more comorbidities and require an early approach after diagnosis to improve prognosis.J. A. Gascón-NavarroM. J. De La Torre-AguilarJ. A. Fernández-RamosJ. Torres-BorregoJ. L. Pérez-NaveroBMCarticlePediatricsRJ1-570ENItalian Journal of Pediatrics, Vol 47, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pediatrics RJ1-570
spellingShingle	Pediatrics RJ1-570 J. A. Gascón-Navarro M. J. De La Torre-Aguilar J. A. Fernández-Ramos J. Torres-Borrego J. L. Pérez-Navero Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital
description	Abstract Introduction Neuromuscular diseases include a large group of heterogeneous and rare pathologies that affect different components of the motor unit. It is essential to optimize resources to know the prevalence of comorbidities in the most frequent groups to establish an early multidisciplinary approach in a specialized setting. Patients and methods Retrospective descriptive study of pediatric and adolescent patients with neuromuscular diseases (NMDs). The Inclusion criteria were NMDs patients with motor neuron involvement divided into three groups, depending on the affected component of the motor unit. Group I: involvement of the motor neuron; Group II: peripheral neuropathies; Group III: myopathies. Demographic variables, association with comorbidities, need for respiratory support, and rehabilitative treatment were collected in each group. Results Ninety-six patients who met the inclusion criteria were studied. In group I, when compared to the other two groups, a higher incidence of scoliosis (68.3%, p = 0.011), deformity of the rib cage (31.3%, p = 0.0001), chronic respiratory insufficiency (62.5%, p = 0.001) and bronchial aspiration (12.5%, p = 0.03) was detected. In this group, 50%of the patients required non-invasive mechanical ventilation (p = 0.0001). The in-hospital requirement for respiratory physiotherapy was higher in group I (75%, p = 0.001). We observed a higher incidence of scoliosis in Group III compared to Group II. Conclusions Neuromuscular diseases with motor neuron involvement present more comorbidities and require an early approach after diagnosis to improve prognosis.
format	article
author	J. A. Gascón-Navarro M. J. De La Torre-Aguilar J. A. Fernández-Ramos J. Torres-Borrego J. L. Pérez-Navero
author_facet	J. A. Gascón-Navarro M. J. De La Torre-Aguilar J. A. Fernández-Ramos J. Torres-Borrego J. L. Pérez-Navero
author_sort	J. A. Gascón-Navarro
title	Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital
title_short	Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital
title_full	Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital
title_fullStr	Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital
title_full_unstemmed	Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital
title_sort	experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital
publisher	BMC
publishDate	2021
url	https://doaj.org/article/ff9969669f494452afbd90dba146223f
work_keys_str_mv	AT jagasconnavarro experienceinneuromusculardiseasesinchildrenandadolescentsandtheircomorbiditiesinatertiaryhospital AT mjdelatorreaguilar experienceinneuromusculardiseasesinchildrenandadolescentsandtheircomorbiditiesinatertiaryhospital AT jafernandezramos experienceinneuromusculardiseasesinchildrenandadolescentsandtheircomorbiditiesinatertiaryhospital AT jtorresborrego experienceinneuromusculardiseasesinchildrenandadolescentsandtheircomorbiditiesinatertiaryhospital AT jlpereznavero experienceinneuromusculardiseasesinchildrenandadolescentsandtheircomorbiditiesinatertiaryhospital
_version_	1718418864401809408

Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital

Ejemplares similares