Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies

Abstract Currently, there are increasing concerns about the possibility of a new epidemic due to emerging reports of Mayaro virus (MAYV) fever outbreaks in areas of South and Central America. Haemagogus mosquitoes, the primary sylvan vectors of MAYV are poorly characterized and a better understandin...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Renee Ali, Jayaraman Jayaraj, Azad Mohammed, Chinnadurai Chinnaraja, Christine V. F. Carrington, David W. Severson, Adesh Ramsubhag
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ff9bf444753544e2879700b59f170400
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ff9bf444753544e2879700b59f170400
record_format	dspace
spelling	oai:doaj.org-article:ff9bf444753544e2879700b59f1704002021-12-02T15:10:54ZCharacterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies10.1038/s41598-021-95842-62045-2322https://doaj.org/article/ff9bf444753544e2879700b59f1704002021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95842-6https://doaj.org/toc/2045-2322Abstract Currently, there are increasing concerns about the possibility of a new epidemic due to emerging reports of Mayaro virus (MAYV) fever outbreaks in areas of South and Central America. Haemagogus mosquitoes, the primary sylvan vectors of MAYV are poorly characterized and a better understanding of the mosquito’s viral transmission dynamics and interactions with MAYV and other microorganisms would be important in devising effective control strategies. In this study, a metatranscriptomic based approach was utilized to determine the prevalence of RNA viruses in field-caught mosquitoes morphologically identified as Haemagogus janthinomys from twelve (12) forest locations in Trinidad, West Indies. Known insect specific viruses including the Phasi Charoen-like and Humaiata-Tubiacanga virus dominated the virome of the mosquitoes throughout sampling locations while other viruses such as the avian leukosis virus, MAYV and several unclassified viruses had a narrower distribution. Additionally, assembled contigs from the Ecclesville location suggests the presence of a unique uncharacterized picorna-like virus. Mapping of RNA sequencing reads to reference mitochondrial sequences of potential feeding host animals showed hits against avian and rodent sequences, which putatively adds to the growing body of evidence of a potentially wide feeding host-range for the Haemagogus mosquito vector.Renee AliJayaraman JayarajAzad MohammedChinnadurai ChinnarajaChristine V. F. CarringtonDavid W. SeversonAdesh RamsubhagNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Renee Ali Jayaraman Jayaraj Azad Mohammed Chinnadurai Chinnaraja Christine V. F. Carrington David W. Severson Adesh Ramsubhag Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies
description	Abstract Currently, there are increasing concerns about the possibility of a new epidemic due to emerging reports of Mayaro virus (MAYV) fever outbreaks in areas of South and Central America. Haemagogus mosquitoes, the primary sylvan vectors of MAYV are poorly characterized and a better understanding of the mosquito’s viral transmission dynamics and interactions with MAYV and other microorganisms would be important in devising effective control strategies. In this study, a metatranscriptomic based approach was utilized to determine the prevalence of RNA viruses in field-caught mosquitoes morphologically identified as Haemagogus janthinomys from twelve (12) forest locations in Trinidad, West Indies. Known insect specific viruses including the Phasi Charoen-like and Humaiata-Tubiacanga virus dominated the virome of the mosquitoes throughout sampling locations while other viruses such as the avian leukosis virus, MAYV and several unclassified viruses had a narrower distribution. Additionally, assembled contigs from the Ecclesville location suggests the presence of a unique uncharacterized picorna-like virus. Mapping of RNA sequencing reads to reference mitochondrial sequences of potential feeding host animals showed hits against avian and rodent sequences, which putatively adds to the growing body of evidence of a potentially wide feeding host-range for the Haemagogus mosquito vector.
format	article
author	Renee Ali Jayaraman Jayaraj Azad Mohammed Chinnadurai Chinnaraja Christine V. F. Carrington David W. Severson Adesh Ramsubhag
author_facet	Renee Ali Jayaraman Jayaraj Azad Mohammed Chinnadurai Chinnaraja Christine V. F. Carrington David W. Severson Adesh Ramsubhag
author_sort	Renee Ali
title	Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies
title_short	Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies
title_full	Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies
title_fullStr	Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies
title_full_unstemmed	Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies
title_sort	characterization of the virome associated with haemagogus mosquitoes in trinidad, west indies
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ff9bf444753544e2879700b59f170400
work_keys_str_mv	AT reneeali characterizationoftheviromeassociatedwithhaemagogusmosquitoesintrinidadwestindies AT jayaramanjayaraj characterizationoftheviromeassociatedwithhaemagogusmosquitoesintrinidadwestindies AT azadmohammed characterizationoftheviromeassociatedwithhaemagogusmosquitoesintrinidadwestindies AT chinnaduraichinnaraja characterizationoftheviromeassociatedwithhaemagogusmosquitoesintrinidadwestindies AT christinevfcarrington characterizationoftheviromeassociatedwithhaemagogusmosquitoesintrinidadwestindies AT davidwseverson characterizationoftheviromeassociatedwithhaemagogusmosquitoesintrinidadwestindies AT adeshramsubhag characterizationoftheviromeassociatedwithhaemagogusmosquitoesintrinidadwestindies
_version_	1718387670940385280

Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies

Ejemplares similares