Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements

It is commonly thought that horizontal transfer of most bacterial chromosomal genes is limited, in comparison with the frequent transfer of mobile genetic elements. Humphrey et al. show that, actually, phage-mediated lateral transduction of core chromosomal genes can be more efficient than the trans...

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Main Authors: Suzanne Humphrey, Alfred Fillol-Salom, Nuria Quiles-Puchalt, Rodrigo Ibarra-Chávez, Andreas F. Haag, John Chen, José R. Penadés
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/ff9c8f8cf68d45bebb954b3a88c38374
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Summary:It is commonly thought that horizontal transfer of most bacterial chromosomal genes is limited, in comparison with the frequent transfer of mobile genetic elements. Humphrey et al. show that, actually, phage-mediated lateral transduction of core chromosomal genes can be more efficient than the transfer of mobile genetic elements via conjugation or generalized transduction.