Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL
3-Poly-phosphoinositides (PIP<sub>3</sub>) regulate cell survival, division, and migration. Both PI3-kinase (phosphoinositide-3-kinase) and PTEN (phosphatase and tensin-homolog in chromosome 10) control PIP<sub>3</sub> levels, but the mechanisms connecting PI3-kinase and PTEN...
Guardado en:
Autores principales: | Manuel Olazábal-Morán, Miriam Sánchez-Ortega, Laura Martínez-Muñoz, Carmen Hernández, Manuel S. Rodríguez, Mario Mellado, Ana C. Carrera |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/ffa2fdd3b6c6481f85c696403eaaae8b |
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