The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis
Chronic low-grade inflammation has been suspected to promote atherosclerosis. Here, Geng et al. show that sustained low-grade inflammation promotes atherosclerosis in mice via monocyte programing that involves a coupled disruption of IRAK-M regulation and induction of miR-24.
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Nature Portfolio
2016
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oai:doaj.org-article:ffa51fe5e51e4e3e90bbf675912cbc4a2021-12-02T15:35:45ZThe persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis10.1038/ncomms134362041-1723https://doaj.org/article/ffa51fe5e51e4e3e90bbf675912cbc4a2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13436https://doaj.org/toc/2041-1723Chronic low-grade inflammation has been suspected to promote atherosclerosis. Here, Geng et al. show that sustained low-grade inflammation promotes atherosclerosis in mice via monocyte programing that involves a coupled disruption of IRAK-M regulation and induction of miR-24.Shuo GengKeqiang ChenRuoxi YuanLiang PengUrmila MaitraNa DiaoChun ChenYao ZhangYuan HuChen-Feng QiSusan PierceWenhua LingHuabao XiongLiwu LiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Shuo Geng Keqiang Chen Ruoxi Yuan Liang Peng Urmila Maitra Na Diao Chun Chen Yao Zhang Yuan Hu Chen-Feng Qi Susan Pierce Wenhua Ling Huabao Xiong Liwu Li The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis |
| description |
Chronic low-grade inflammation has been suspected to promote atherosclerosis. Here, Geng et al. show that sustained low-grade inflammation promotes atherosclerosis in mice via monocyte programing that involves a coupled disruption of IRAK-M regulation and induction of miR-24. |
| format |
article |
| author |
Shuo Geng Keqiang Chen Ruoxi Yuan Liang Peng Urmila Maitra Na Diao Chun Chen Yao Zhang Yuan Hu Chen-Feng Qi Susan Pierce Wenhua Ling Huabao Xiong Liwu Li |
| author_facet |
Shuo Geng Keqiang Chen Ruoxi Yuan Liang Peng Urmila Maitra Na Diao Chun Chen Yao Zhang Yuan Hu Chen-Feng Qi Susan Pierce Wenhua Ling Huabao Xiong Liwu Li |
| author_sort |
Shuo Geng |
| title |
The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis |
| title_short |
The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis |
| title_full |
The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis |
| title_fullStr |
The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis |
| title_full_unstemmed |
The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis |
| title_sort |
persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/ffa51fe5e51e4e3e90bbf675912cbc4a |
| work_keys_str_mv |
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1718386512718987264 |