The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis

Chronic low-grade inflammation has been suspected to promote atherosclerosis. Here, Geng et al. show that sustained low-grade inflammation promotes atherosclerosis in mice via monocyte programing that involves a coupled disruption of IRAK-M regulation and induction of miR-24.

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Auteurs principaux: Shuo Geng, Keqiang Chen, Ruoxi Yuan, Liang Peng, Urmila Maitra, Na Diao, Chun Chen, Yao Zhang, Yuan Hu, Chen-Feng Qi, Susan Pierce, Wenhua Ling, Huabao Xiong, Liwu Li
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/ffa51fe5e51e4e3e90bbf675912cbc4a
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