Compartmentalised RNA catalysis in membrane-free coacervate protocells

Phase separation of mixtures of oppositely charged polymers provides a simple and direct route to compartmentalisation via coacervation. Here authors demonstrate that a coacervate microenvironment supports RNA catalysis whilst selectively sequestering RNA based on length.

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Autores principales:	Björn Drobot, Juan M. Iglesias-Artola, Kristian Le Vay, Viktoria Mayr, Mrityunjoy Kar, Moritz Kreysing, Hannes Mutschler, T-Y Dora Tang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ffa9ae58dd1c47ec95dba2093bd693d4
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spelling	oai:doaj.org-article:ffa9ae58dd1c47ec95dba2093bd693d42021-12-02T16:50:07ZCompartmentalised RNA catalysis in membrane-free coacervate protocells10.1038/s41467-018-06072-w2041-1723https://doaj.org/article/ffa9ae58dd1c47ec95dba2093bd693d42018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06072-whttps://doaj.org/toc/2041-1723Phase separation of mixtures of oppositely charged polymers provides a simple and direct route to compartmentalisation via coacervation. Here authors demonstrate that a coacervate microenvironment supports RNA catalysis whilst selectively sequestering RNA based on length.Björn DrobotJuan M. Iglesias-ArtolaKristian Le VayViktoria MayrMrityunjoy KarMoritz KreysingHannes MutschlerT-Y Dora TangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Björn Drobot Juan M. Iglesias-Artola Kristian Le Vay Viktoria Mayr Mrityunjoy Kar Moritz Kreysing Hannes Mutschler T-Y Dora Tang Compartmentalised RNA catalysis in membrane-free coacervate protocells
description	Phase separation of mixtures of oppositely charged polymers provides a simple and direct route to compartmentalisation via coacervation. Here authors demonstrate that a coacervate microenvironment supports RNA catalysis whilst selectively sequestering RNA based on length.
format	article
author	Björn Drobot Juan M. Iglesias-Artola Kristian Le Vay Viktoria Mayr Mrityunjoy Kar Moritz Kreysing Hannes Mutschler T-Y Dora Tang
author_facet	Björn Drobot Juan M. Iglesias-Artola Kristian Le Vay Viktoria Mayr Mrityunjoy Kar Moritz Kreysing Hannes Mutschler T-Y Dora Tang
author_sort	Björn Drobot
title	Compartmentalised RNA catalysis in membrane-free coacervate protocells
title_short	Compartmentalised RNA catalysis in membrane-free coacervate protocells
title_full	Compartmentalised RNA catalysis in membrane-free coacervate protocells
title_fullStr	Compartmentalised RNA catalysis in membrane-free coacervate protocells
title_full_unstemmed	Compartmentalised RNA catalysis in membrane-free coacervate protocells
title_sort	compartmentalised rna catalysis in membrane-free coacervate protocells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/ffa9ae58dd1c47ec95dba2093bd693d4
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Compartmentalised RNA catalysis in membrane-free coacervate protocells

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