Antifibrinolytic agents for the prevention of postpartum hemorrhage

Acute obstetric coagulopathy secondary to postpartum hemorrhage (PPH) is associated with poor outcome. There is evidence that Tranexamic Acid (TA), an antifibrinolytic drug, is an efficient tool of patient blood management in association with uterotonics to reduce mortality due to postpartum hemorrh...

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Autores principales:	Anne-Sophie Bouthors, Sixtine Gilliot, David Faraoni, Loic Sentilhes
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Tranexamic acid Postpartum hemorrhage Fibrinolysis Prevention Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/ffb3f0723e5442a4b0f5522cb21bad90
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spelling	oai:doaj.org-article:ffb3f0723e5442a4b0f5522cb21bad902021-11-20T05:14:41ZAntifibrinolytic agents for the prevention of postpartum hemorrhage2666-572710.1016/j.tru.2021.100089https://doaj.org/article/ffb3f0723e5442a4b0f5522cb21bad902021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666572721000584https://doaj.org/toc/2666-5727Acute obstetric coagulopathy secondary to postpartum hemorrhage (PPH) is associated with poor outcome. There is evidence that Tranexamic Acid (TA), an antifibrinolytic drug, is an efficient tool of patient blood management in association with uterotonics to reduce mortality due to postpartum hemorrhage (PPH). Recent trials investigated its preventive administration before PPH. This review summarizes their major results and introduces the ongoing debate on a systematic prophylaxis of coagulopathy before PPH occurs.Anne-Sophie BouthorsSixtine GilliotDavid FaraoniLoic SentilhesElsevierarticleTranexamic acidPostpartum hemorrhageFibrinolysisPreventionDiseases of the circulatory (Cardiovascular) systemRC666-701ENThrombosis Update, Vol 5, Iss , Pp 100089- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Tranexamic acid Postpartum hemorrhage Fibrinolysis Prevention Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Tranexamic acid Postpartum hemorrhage Fibrinolysis Prevention Diseases of the circulatory (Cardiovascular) system RC666-701 Anne-Sophie Bouthors Sixtine Gilliot David Faraoni Loic Sentilhes Antifibrinolytic agents for the prevention of postpartum hemorrhage
description	Acute obstetric coagulopathy secondary to postpartum hemorrhage (PPH) is associated with poor outcome. There is evidence that Tranexamic Acid (TA), an antifibrinolytic drug, is an efficient tool of patient blood management in association with uterotonics to reduce mortality due to postpartum hemorrhage (PPH). Recent trials investigated its preventive administration before PPH. This review summarizes their major results and introduces the ongoing debate on a systematic prophylaxis of coagulopathy before PPH occurs.
format	article
author	Anne-Sophie Bouthors Sixtine Gilliot David Faraoni Loic Sentilhes
author_facet	Anne-Sophie Bouthors Sixtine Gilliot David Faraoni Loic Sentilhes
author_sort	Anne-Sophie Bouthors
title	Antifibrinolytic agents for the prevention of postpartum hemorrhage
title_short	Antifibrinolytic agents for the prevention of postpartum hemorrhage
title_full	Antifibrinolytic agents for the prevention of postpartum hemorrhage
title_fullStr	Antifibrinolytic agents for the prevention of postpartum hemorrhage
title_full_unstemmed	Antifibrinolytic agents for the prevention of postpartum hemorrhage
title_sort	antifibrinolytic agents for the prevention of postpartum hemorrhage
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/ffb3f0723e5442a4b0f5522cb21bad90
work_keys_str_mv	AT annesophiebouthors antifibrinolyticagentsforthepreventionofpostpartumhemorrhage AT sixtinegilliot antifibrinolyticagentsforthepreventionofpostpartumhemorrhage AT davidfaraoni antifibrinolyticagentsforthepreventionofpostpartumhemorrhage AT loicsentilhes antifibrinolyticagentsforthepreventionofpostpartumhemorrhage
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Antifibrinolytic agents for the prevention of postpartum hemorrhage

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