Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study

Background: This study aimed to determine whether the prevalence of acute vertebral osteoporotic compression fractures (VOCF) in the elderly population is related to the distribution of muscles and fat in the human body.Methods: Data of acute VOCF and non-VOCF patients presenting at our institution...

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Autores principales:	Younghun Lee, Ho-Jae Lee, Siyeong Yoon, Jaeyeon Shin, Kyung-Chae Park, So-young Lee, Soonchul Lee
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	sarcopenic obesity osteoporosis vertebral compression fracture bone mineral density body composition test Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/ffb43808a493413e9dea2100c9554f9b
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spelling	oai:doaj.org-article:ffb43808a493413e9dea2100c9554f9b2021-12-03T05:36:42ZAssociation Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study2296-858X10.3389/fmed.2021.790135https://doaj.org/article/ffb43808a493413e9dea2100c9554f9b2021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.790135/fullhttps://doaj.org/toc/2296-858XBackground: This study aimed to determine whether the prevalence of acute vertebral osteoporotic compression fractures (VOCF) in the elderly population is related to the distribution of muscles and fat in the human body.Methods: Data of acute VOCF and non-VOCF patients presenting at our institution between January 2018 and May 2020 were analyzed. Patients aged 65 years and older, who underwent body composition test and dual-energy X-ray absorptiometry at the same time were enrolled. After applying exclusion criteria, patients were divided into four groups: normal, sarcopenia without obesity, obesity without sarcopenia, and sarcopenic obesity. Body mass index ≥25 kg/m2 was considered obesity, and sarcopenia was defined as skeletal muscle index lower than 7.0 kg/m2 in males and 5.4 kg/m2 in females. The VOCF rate was analyzed between the groups.Discussion: A total of 461 patients were included, of whom 103 were males. Among them, 163 (35.36%) had normal body composition, 151 (32.75%) had sarcopenia without obesity, 110 (23.86%) had obesity without sarcopenia, and 37 (8.03%) had sarcopenic obesity. The sarcopenic obesity group had the highest rate of acute VOCF (37.8%), which was statistically significant. Specifically, females with sarcopenic obesity and sarcopenia without obesity had significantly higher acute VOCF rates compared to those with normal body compositions. Multivariate analysis showed that sarcopenic obesity was significantly associated with acute VOCF rate overall, as well as in females.Conclusion: Sarcopenic obesity is strongly associated with acute VOCF, especially in females, and it could be an essential criterion for the prevention of acute VOCF.Younghun LeeHo-Jae LeeSiyeong YoonJaeyeon ShinKyung-Chae ParkSo-young LeeSoonchul LeeFrontiers Media S.A.articlesarcopenic obesityosteoporosisvertebral compression fracturebone mineral densitybody composition testMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	sarcopenic obesity osteoporosis vertebral compression fracture bone mineral density body composition test Medicine (General) R5-920
spellingShingle	sarcopenic obesity osteoporosis vertebral compression fracture bone mineral density body composition test Medicine (General) R5-920 Younghun Lee Ho-Jae Lee Siyeong Yoon Jaeyeon Shin Kyung-Chae Park So-young Lee Soonchul Lee Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study
description	Background: This study aimed to determine whether the prevalence of acute vertebral osteoporotic compression fractures (VOCF) in the elderly population is related to the distribution of muscles and fat in the human body.Methods: Data of acute VOCF and non-VOCF patients presenting at our institution between January 2018 and May 2020 were analyzed. Patients aged 65 years and older, who underwent body composition test and dual-energy X-ray absorptiometry at the same time were enrolled. After applying exclusion criteria, patients were divided into four groups: normal, sarcopenia without obesity, obesity without sarcopenia, and sarcopenic obesity. Body mass index ≥25 kg/m2 was considered obesity, and sarcopenia was defined as skeletal muscle index lower than 7.0 kg/m2 in males and 5.4 kg/m2 in females. The VOCF rate was analyzed between the groups.Discussion: A total of 461 patients were included, of whom 103 were males. Among them, 163 (35.36%) had normal body composition, 151 (32.75%) had sarcopenia without obesity, 110 (23.86%) had obesity without sarcopenia, and 37 (8.03%) had sarcopenic obesity. The sarcopenic obesity group had the highest rate of acute VOCF (37.8%), which was statistically significant. Specifically, females with sarcopenic obesity and sarcopenia without obesity had significantly higher acute VOCF rates compared to those with normal body compositions. Multivariate analysis showed that sarcopenic obesity was significantly associated with acute VOCF rate overall, as well as in females.Conclusion: Sarcopenic obesity is strongly associated with acute VOCF, especially in females, and it could be an essential criterion for the prevention of acute VOCF.
format	article
author	Younghun Lee Ho-Jae Lee Siyeong Yoon Jaeyeon Shin Kyung-Chae Park So-young Lee Soonchul Lee
author_facet	Younghun Lee Ho-Jae Lee Siyeong Yoon Jaeyeon Shin Kyung-Chae Park So-young Lee Soonchul Lee
author_sort	Younghun Lee
title	Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study
title_short	Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study
title_full	Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study
title_fullStr	Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study
title_full_unstemmed	Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study
title_sort	association between overweight sarcopenic population and acute vertebral osteoporotic compression fractures in females: retrospective, cross-sectional study
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/ffb43808a493413e9dea2100c9554f9b
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Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study

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