Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain
Abstract Diabetic nephropathy (DN) is the leading cause of chronic kidney disease. Animal models are essential tools for designing new strategies to prevent DN. C57Bl/6 (B6) mice are widely used for transgenic mouse models, but are relatively resistant to DN. This study aims to identify the most eff...
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Main Authors: | Melissa Uil, Angelique M. L. Scantlebery, Loes M. Butter, Per W. B. Larsen, Onno J. de Boer, Jaklien C. Leemans, Sandrine Florquin, Joris J. T. H. Roelofs |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/ffb9045537bd4a1e9e4e57840a74a191 |
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