Level of sustained glycemic control and associated factors among patients with diabetes mellitus in Ethiopia: a hospital-based cross-sectional study

Solomon Mekonnen Abebe,1 Yemane Berhane,2 Alemayehu Worku,3 Shitaye Alemu,1 Nebiyu Mesfin1 1University of Gondar, College of Medicine and Health Sciences, School of Medicine, Gondar, Ethiopia; 2Addis Continental Institute of Public Health, Addis Ababa, Ethiopia; 3School of Public Health, Addis Abab...

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Main Authors: Abebe SM, Berhane Y, Worku A, Alemu S, Mesfin N
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Language:EN
Published: Dove Medical Press 2015
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spelling oai:doaj.org-article:ffba63aa7ddd40d98ee5462ccdc7fa9f2021-12-02T03:21:23ZLevel of sustained glycemic control and associated factors among patients with diabetes mellitus in Ethiopia: a hospital-based cross-sectional study1178-7007https://doaj.org/article/ffba63aa7ddd40d98ee5462ccdc7fa9f2015-01-01T00:00:00Zhttp://www.dovepress.com/level-of-sustained-glycemic-control-and-associated-factors-among-patie-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007 Solomon Mekonnen Abebe,1 Yemane Berhane,2 Alemayehu Worku,3 Shitaye Alemu,1 Nebiyu Mesfin1 1University of Gondar, College of Medicine and Health Sciences, School of Medicine, Gondar, Ethiopia; 2Addis Continental Institute of Public Health, Addis Ababa, Ethiopia; 3School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia Background: The level of sustained glycemic control in patients with diabetes mellitus (DM) is a major determinant of the occurrence of both acute and chronic complications. However, information about the level of glycemic control among patients in the follow-up care at the University of Gondar Referral Hospital is scanty. The study assessed the degree of glycemic control and associated factors among diabetic patients in the study area. Method: A hospital-based cross-sectional study was conducted at the University of Gondar Referral Hospital. All diabetic patients aged ≥18 years who visited the Diabetes Clinic in January and February 2013 for follow-up medical evaluation and medication participated in the study. Patients with glycosylated hemoglobin test (HbA1c) of ≥7% were classified as having a poor level of glycemic control. Propensity score was used to estimate the treatment effect. Multivariable logistic regression analysis was applied to determine the associated factors. Result: Two hundred and fifty three (64.7%) of the 391 diabetic patients included in the study had a poor level of glycemic control, as evidenced by HbA1c ≥7%. Poor glycemic control was much higher among Type 1 patients (82.9%) compared with Type 2 patients (57.5%). Being on insulin treatment (AOR =2.51; 95% CI =1.25, 5.04) and reporting poor medication adherence (AOR =3.19; 95% CI =1.76, 5.80) were found to be associated with poor glycemic control among Type 2 DM patients. High waist circumference was inversely associated with a poor level of glycemic control in Type 1 DM patients (AOR =0.05; 95% CI =0.01, 0.85). Conclusion: The proportion of diabetic patients with a poor level of glycemic control is high. We recommend a comprehensive intervention to improve the overall treatment adherence with special attention to DM patients receiving insulin. Keywords: glycemic control, HbA1c, waist circumference, diabetes mellitus, BMI Abebe SMBerhane YWorku AAlemu SMesfin NDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2015, Iss default, Pp 65-71 (2015)
institution DOAJ
collection DOAJ
language EN
topic Specialties of internal medicine
RC581-951
spellingShingle Specialties of internal medicine
RC581-951
Abebe SM
Berhane Y
Worku A
Alemu S
Mesfin N
Level of sustained glycemic control and associated factors among patients with diabetes mellitus in Ethiopia: a hospital-based cross-sectional study
description Solomon Mekonnen Abebe,1 Yemane Berhane,2 Alemayehu Worku,3 Shitaye Alemu,1 Nebiyu Mesfin1 1University of Gondar, College of Medicine and Health Sciences, School of Medicine, Gondar, Ethiopia; 2Addis Continental Institute of Public Health, Addis Ababa, Ethiopia; 3School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia Background: The level of sustained glycemic control in patients with diabetes mellitus (DM) is a major determinant of the occurrence of both acute and chronic complications. However, information about the level of glycemic control among patients in the follow-up care at the University of Gondar Referral Hospital is scanty. The study assessed the degree of glycemic control and associated factors among diabetic patients in the study area. Method: A hospital-based cross-sectional study was conducted at the University of Gondar Referral Hospital. All diabetic patients aged ≥18 years who visited the Diabetes Clinic in January and February 2013 for follow-up medical evaluation and medication participated in the study. Patients with glycosylated hemoglobin test (HbA1c) of ≥7% were classified as having a poor level of glycemic control. Propensity score was used to estimate the treatment effect. Multivariable logistic regression analysis was applied to determine the associated factors. Result: Two hundred and fifty three (64.7%) of the 391 diabetic patients included in the study had a poor level of glycemic control, as evidenced by HbA1c ≥7%. Poor glycemic control was much higher among Type 1 patients (82.9%) compared with Type 2 patients (57.5%). Being on insulin treatment (AOR =2.51; 95% CI =1.25, 5.04) and reporting poor medication adherence (AOR =3.19; 95% CI =1.76, 5.80) were found to be associated with poor glycemic control among Type 2 DM patients. High waist circumference was inversely associated with a poor level of glycemic control in Type 1 DM patients (AOR =0.05; 95% CI =0.01, 0.85). Conclusion: The proportion of diabetic patients with a poor level of glycemic control is high. We recommend a comprehensive intervention to improve the overall treatment adherence with special attention to DM patients receiving insulin. Keywords: glycemic control, HbA1c, waist circumference, diabetes mellitus, BMI 
format article
author Abebe SM
Berhane Y
Worku A
Alemu S
Mesfin N
author_facet Abebe SM
Berhane Y
Worku A
Alemu S
Mesfin N
author_sort Abebe SM
title Level of sustained glycemic control and associated factors among patients with diabetes mellitus in Ethiopia: a hospital-based cross-sectional study
title_short Level of sustained glycemic control and associated factors among patients with diabetes mellitus in Ethiopia: a hospital-based cross-sectional study
title_full Level of sustained glycemic control and associated factors among patients with diabetes mellitus in Ethiopia: a hospital-based cross-sectional study
title_fullStr Level of sustained glycemic control and associated factors among patients with diabetes mellitus in Ethiopia: a hospital-based cross-sectional study
title_full_unstemmed Level of sustained glycemic control and associated factors among patients with diabetes mellitus in Ethiopia: a hospital-based cross-sectional study
title_sort level of sustained glycemic control and associated factors among patients with diabetes mellitus in ethiopia: a hospital-based cross-sectional study
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/ffba63aa7ddd40d98ee5462ccdc7fa9f
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