Patterns of genomic evolution in advanced melanoma
As melanoma progresses, it evolves. Here, in advanced melanoma the authors study genomic evolution, highlighting trunk mutations dominated by the ultraviolet damage signature, common late truncal whole-genome duplication events, as well as selective copy number gain of mutant BRAF.
Guardado en:
Autores principales: | E. Birkeland, S. Zhang, D. Poduval, J. Geisler, S. Nakken, D. Vodak, L. A. Meza-Zepeda, E. Hovig, O. Myklebost, S. Knappskog, P. E. Lønning |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ffbb2b2a90434988a7693775c83b0b50 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Punctuated evolution of canonical genomic aberrations in uveal melanoma
por: Matthew G. Field, et al.
Publicado: (2018) -
Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling
por: Ismael A. Vergara, et al.
Publicado: (2021) -
Treatment of Advanced Metastatic Melanoma
por: Pietro Quaglino, et al.
Publicado: (2021) -
Multiregional genetic evolution of metastatic uveal melanoma
por: Daniel A. Rodriguez, et al.
Publicado: (2021) -
Predictors of responses to immune checkpoint blockade in advanced melanoma
por: N. Jacquelot, et al.
Publicado: (2017)