Patterns of genomic evolution in advanced melanoma

As melanoma progresses, it evolves. Here, in advanced melanoma the authors study genomic evolution, highlighting trunk mutations dominated by the ultraviolet damage signature, common late truncal whole-genome duplication events, as well as selective copy number gain of mutant BRAF.

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Detalles Bibliográficos
Autores principales: E. Birkeland, S. Zhang, D. Poduval, J. Geisler, S. Nakken, D. Vodak, L. A. Meza-Zepeda, E. Hovig, O. Myklebost, S. Knappskog, P. E. Lønning
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/ffbb2b2a90434988a7693775c83b0b50
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