Anisotropic ESCRT-III architecture governs helical membrane tube formation

Anisotropic ESCRT-III architecture governs helical membrane tube formation

ESCRT-III proteins assemble into ubiquitous membrane-remodeling polymers during many cellular processes. Here, the authors use cryo-ET, cryo-EM and mathematical modeling to reveal how the shape of the helical membrane tube arises from the assembly of two distinct bundles of helical filaments.

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Autores principales: Joachim Moser von Filseck, Luca Barberi, Nathaniel Talledge, Isabel E. Johnson, Adam Frost, Martin Lenz, Aurélien Roux
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/ffbbce3ca19e4ccbb4dd18d0ff5b656f
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