A large size-selective DNA nanopore with sensing applications

Artificial nanopores can perform selective gating of molecules analogous to transmembrane proteins. Here, the authors design a DNA origami pore with a controllable lid for size-selective gating and translocation of macromolecules and evaluate its biosensing properties by single particle assay.

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Bibliographic Details
Main Authors:	Rasmus P. Thomsen, Mette Galsgaard Malle, Anders Hauge Okholm, Swati Krishnan, Søren S.-R. Bohr, Rasmus Schøler Sørensen, Oliver Ries, Stefan Vogel, Friedrich C. Simmel, Nikos S. Hatzakis, Jørgen Kjems
Format:	article
Language:	EN
Published:	Nature Portfolio 2019
Subjects:	Science Q
Online Access:	https://doaj.org/article/ffbfe203a3124a59974af877ed67471a
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spelling	oai:doaj.org-article:ffbfe203a3124a59974af877ed67471a2021-12-02T15:35:15ZA large size-selective DNA nanopore with sensing applications10.1038/s41467-019-13284-12041-1723https://doaj.org/article/ffbfe203a3124a59974af877ed67471a2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13284-1https://doaj.org/toc/2041-1723Artificial nanopores can perform selective gating of molecules analogous to transmembrane proteins. Here, the authors design a DNA origami pore with a controllable lid for size-selective gating and translocation of macromolecules and evaluate its biosensing properties by single particle assay.Rasmus P. ThomsenMette Galsgaard MalleAnders Hauge OkholmSwati KrishnanSøren S.-R. BohrRasmus Schøler SørensenOliver RiesStefan VogelFriedrich C. SimmelNikos S. HatzakisJørgen KjemsNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rasmus P. Thomsen Mette Galsgaard Malle Anders Hauge Okholm Swati Krishnan Søren S.-R. Bohr Rasmus Schøler Sørensen Oliver Ries Stefan Vogel Friedrich C. Simmel Nikos S. Hatzakis Jørgen Kjems A large size-selective DNA nanopore with sensing applications
description	Artificial nanopores can perform selective gating of molecules analogous to transmembrane proteins. Here, the authors design a DNA origami pore with a controllable lid for size-selective gating and translocation of macromolecules and evaluate its biosensing properties by single particle assay.
format	article
author	Rasmus P. Thomsen Mette Galsgaard Malle Anders Hauge Okholm Swati Krishnan Søren S.-R. Bohr Rasmus Schøler Sørensen Oliver Ries Stefan Vogel Friedrich C. Simmel Nikos S. Hatzakis Jørgen Kjems
author_facet	Rasmus P. Thomsen Mette Galsgaard Malle Anders Hauge Okholm Swati Krishnan Søren S.-R. Bohr Rasmus Schøler Sørensen Oliver Ries Stefan Vogel Friedrich C. Simmel Nikos S. Hatzakis Jørgen Kjems
author_sort	Rasmus P. Thomsen
title	A large size-selective DNA nanopore with sensing applications
title_short	A large size-selective DNA nanopore with sensing applications
title_full	A large size-selective DNA nanopore with sensing applications
title_fullStr	A large size-selective DNA nanopore with sensing applications
title_full_unstemmed	A large size-selective DNA nanopore with sensing applications
title_sort	large size-selective dna nanopore with sensing applications
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ffbfe203a3124a59974af877ed67471a
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A large size-selective DNA nanopore with sensing applications

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