Two-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in Japan

Tetsuji Cho,1,2 Hideki Negoro,3 Yasuhiro Saka,1 Masayuki Morikawa,1,2 Toshifumi Kishimoto2 1Mie Prefectural Mental Care Center, Tsu-Shi, Mie, 2Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 3Faculty of Education, Nara University of Education, Nara, Japan Bac...

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Autores principales:	Cho T, Negoro H, Saka Y, Morikawa M, Kishimoto T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	alcohol dependence 3 chief guidelines for sobriety (3CGS) disulfiram self-help group recovery Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/ffc63d1db42049cd8dc8ba66d7da884e
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spelling	oai:doaj.org-article:ffc63d1db42049cd8dc8ba66d7da884e2021-12-02T06:26:39ZTwo-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in Japan1178-2021https://doaj.org/article/ffc63d1db42049cd8dc8ba66d7da884e2016-08-01T00:00:00Zhttps://www.dovepress.com/two-year-prognosis-after-residential-treatment-for-patients-with-alcoh-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Tetsuji Cho,1,2 Hideki Negoro,3 Yasuhiro Saka,1 Masayuki Morikawa,1,2 Toshifumi Kishimoto2 1Mie Prefectural Mental Care Center, Tsu-Shi, Mie, 2Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 3Faculty of Education, Nara University of Education, Nara, Japan Background: In Japan, the three chief traditional guidelines for sobriety (3CGS) are regular medical checkups, participation in self-help groups, and pharmacotherapy with antidipsotropics. However, the official record of the origins of 3CGS is not clear. The aim of this current study was to assess 3CGS by an examination of the prognosis of patients with alcohol dependence 2 years after their discharge from a residential treatment program. Subjects and methods: The association between subjects’ abstinence from alcohol and their regular medical checkups, participation in self-help groups, and treatment with antidipsotropics were prospectively examined. Two years after discharge, the relationship between the 3CGS compliance and abstinence rates was investigated as the primary outcome. In addition, the following were examined as secondary outcomes: the time taken till the first drink after discharge, whether the participants were readmitted to residential treatment, the number of days to readmission, the number of heavy drinking days, and recovery. Results: A total of 98 patients participated. The perfect and partial abstinence rates for patients who followed all the principles of 3CGS were significantly higher than those for patients who followed no guidelines (P<0.05 and P<0.01, respectively). The perfect abstinence rates for patients who had continued attending checkup sessions (P<0.001) and who were taking antidipsotropics (P<0.05) were significantly higher than those for patients who did not follow these components of 3CGS. However, the perfect abstinence rates were not higher for patients who had continued to participate in self-help groups. In addition, the perfect abstinence rate was statistically associated with regular medical checkups (adjusted odds ratio =5.33, 95% confidence interval =1.35–21.0) and participation in self-help groups (adjusted odds ratio =3.79, 95% confidence interval =1.17–12.3). Conclusion: This study, reports the effectiveness of 3CGS for the first time. The recovery rate of alcoholics 2 years after discharge from residential treatment was examined. However, due to the chronic nature of alcoholism, further studies are required to investigate the efficacy of 3CGS beyond 2 years. Keywords: alcohol dependence, three chief guidelines for sobriety (3CGS), disulfiram, self-help group, recoveryCho TNegoro HSaka YMorikawa MKishimoto TDove Medical Pressarticlealcohol dependence3 chief guidelines for sobriety (3CGS)disulfiramself-help grouprecoveryNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2016, Iss Issue 1, Pp 1983-1991 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	alcohol dependence 3 chief guidelines for sobriety (3CGS) disulfiram self-help group recovery Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	alcohol dependence 3 chief guidelines for sobriety (3CGS) disulfiram self-help group recovery Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Cho T Negoro H Saka Y Morikawa M Kishimoto T Two-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in Japan
description	Tetsuji Cho,1,2 Hideki Negoro,3 Yasuhiro Saka,1 Masayuki Morikawa,1,2 Toshifumi Kishimoto2 1Mie Prefectural Mental Care Center, Tsu-Shi, Mie, 2Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 3Faculty of Education, Nara University of Education, Nara, Japan Background: In Japan, the three chief traditional guidelines for sobriety (3CGS) are regular medical checkups, participation in self-help groups, and pharmacotherapy with antidipsotropics. However, the official record of the origins of 3CGS is not clear. The aim of this current study was to assess 3CGS by an examination of the prognosis of patients with alcohol dependence 2 years after their discharge from a residential treatment program. Subjects and methods: The association between subjects’ abstinence from alcohol and their regular medical checkups, participation in self-help groups, and treatment with antidipsotropics were prospectively examined. Two years after discharge, the relationship between the 3CGS compliance and abstinence rates was investigated as the primary outcome. In addition, the following were examined as secondary outcomes: the time taken till the first drink after discharge, whether the participants were readmitted to residential treatment, the number of days to readmission, the number of heavy drinking days, and recovery. Results: A total of 98 patients participated. The perfect and partial abstinence rates for patients who followed all the principles of 3CGS were significantly higher than those for patients who followed no guidelines (P<0.05 and P<0.01, respectively). The perfect abstinence rates for patients who had continued attending checkup sessions (P<0.001) and who were taking antidipsotropics (P<0.05) were significantly higher than those for patients who did not follow these components of 3CGS. However, the perfect abstinence rates were not higher for patients who had continued to participate in self-help groups. In addition, the perfect abstinence rate was statistically associated with regular medical checkups (adjusted odds ratio =5.33, 95% confidence interval =1.35–21.0) and participation in self-help groups (adjusted odds ratio =3.79, 95% confidence interval =1.17–12.3). Conclusion: This study, reports the effectiveness of 3CGS for the first time. The recovery rate of alcoholics 2 years after discharge from residential treatment was examined. However, due to the chronic nature of alcoholism, further studies are required to investigate the efficacy of 3CGS beyond 2 years. Keywords: alcohol dependence, three chief guidelines for sobriety (3CGS), disulfiram, self-help group, recovery
format	article
author	Cho T Negoro H Saka Y Morikawa M Kishimoto T
author_facet	Cho T Negoro H Saka Y Morikawa M Kishimoto T
author_sort	Cho T
title	Two-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in Japan
title_short	Two-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in Japan
title_full	Two-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in Japan
title_fullStr	Two-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in Japan
title_full_unstemmed	Two-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in Japan
title_sort	two-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in japan
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/ffc63d1db42049cd8dc8ba66d7da884e
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Two-year prognosis after residential treatment for patients with alcohol dependence: three chief guidelines for sobriety in Japan

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