Impact of respiratory infectious epidemics on STEMI incidence and care

Abstract The effect of respiratory infectious diseases on STEMI incidence, but also STEMI care is not well understood. The Influenza 2017/2018 epidemic and the COVID-19 pandemic were chosen as observational periods to investigate the effect of respiratory virus diseases on these outcomes in a metrop...

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Autores principales:	S. Macherey, M. M. Meertens, C. Adler, S. Braumann, S. Heyne, T. Tichelbäcker, F. S. Nießen, H. Christ, I. Ahrens, F. M. Baer, F. Eberhardt, M. Horlitz, A. Meissner, J. M. Sinning, S. Baldus, S. Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ffc9d503b5354414a3ffb7a555fd7af2
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spelling	oai:doaj.org-article:ffc9d503b5354414a3ffb7a555fd7af22021-12-05T12:15:45ZImpact of respiratory infectious epidemics on STEMI incidence and care10.1038/s41598-021-02480-z2045-2322https://doaj.org/article/ffc9d503b5354414a3ffb7a555fd7af22021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02480-zhttps://doaj.org/toc/2045-2322Abstract The effect of respiratory infectious diseases on STEMI incidence, but also STEMI care is not well understood. The Influenza 2017/2018 epidemic and the COVID-19 pandemic were chosen as observational periods to investigate the effect of respiratory virus diseases on these outcomes in a metropolitan area with an established STEMI network. We analyzed data on incidence and care during the COVID-19 pandemic, Influenza 2017/2018 epidemic and corresponding seasonal control periods. Three comparisons were performed: (1) COVID-19 pandemic group versus pandemic control group, (2) COVID-19 pandemic group versus Influenza 2017/2018 epidemic group and (3) Influenza 2017/2018 epidemic group versus epidemic control group. We used Student’s t-test, Fisher’s exact test and Chi square test for statistical analysis. 1455 patients were eligible. The daily STEMI incidence was 1.49 during the COVID-19 pandemic, 1.40 for the pandemic season control period, 1.22 during the Influenza 2017/2018 epidemic and 1.28 during the epidemic season control group. Median symptom-to-contact time was 180 min during the COVID-19 pandemic. In the pandemic season control group it was 90 min (p = 0.183), and in the Influenza 2017/2018 cohort it was 90 min, too (p = 0.216). Interval in the epidemic control group was 79 min (p = 0.733). The COVID-19 group had a door-to-balloon time of 49 min, corresponding intervals were 39 min for the pandemic season group (p = 0.038), 37 min for the Influenza 2017/2018 group (p = 0.421), and 38 min for the epidemic season control group (p = 0.429). In-hospital mortality was 6.1% for the COVID-19 group, 5.9% for the Influenza 2017/2018 group (p = 1.0), 11% and 11.2% for the season control groups. The respiratory virus diseases neither resulted in an overall treatment delay, nor did they cause an increase in STEMI mortality or incidence. The registry analysis demonstrated a prolonged door-to-balloon time during the COVID-19 pandemic.S. MachereyM. M. MeertensC. AdlerS. BraumannS. HeyneT. TichelbäckerF. S. NießenH. ChristI. AhrensF. M. BaerF. EberhardtM. HorlitzA. MeissnerJ. M. SinningS. BaldusS. LeeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q S. Macherey M. M. Meertens C. Adler S. Braumann S. Heyne T. Tichelbäcker F. S. Nießen H. Christ I. Ahrens F. M. Baer F. Eberhardt M. Horlitz A. Meissner J. M. Sinning S. Baldus S. Lee Impact of respiratory infectious epidemics on STEMI incidence and care
description	Abstract The effect of respiratory infectious diseases on STEMI incidence, but also STEMI care is not well understood. The Influenza 2017/2018 epidemic and the COVID-19 pandemic were chosen as observational periods to investigate the effect of respiratory virus diseases on these outcomes in a metropolitan area with an established STEMI network. We analyzed data on incidence and care during the COVID-19 pandemic, Influenza 2017/2018 epidemic and corresponding seasonal control periods. Three comparisons were performed: (1) COVID-19 pandemic group versus pandemic control group, (2) COVID-19 pandemic group versus Influenza 2017/2018 epidemic group and (3) Influenza 2017/2018 epidemic group versus epidemic control group. We used Student’s t-test, Fisher’s exact test and Chi square test for statistical analysis. 1455 patients were eligible. The daily STEMI incidence was 1.49 during the COVID-19 pandemic, 1.40 for the pandemic season control period, 1.22 during the Influenza 2017/2018 epidemic and 1.28 during the epidemic season control group. Median symptom-to-contact time was 180 min during the COVID-19 pandemic. In the pandemic season control group it was 90 min (p = 0.183), and in the Influenza 2017/2018 cohort it was 90 min, too (p = 0.216). Interval in the epidemic control group was 79 min (p = 0.733). The COVID-19 group had a door-to-balloon time of 49 min, corresponding intervals were 39 min for the pandemic season group (p = 0.038), 37 min for the Influenza 2017/2018 group (p = 0.421), and 38 min for the epidemic season control group (p = 0.429). In-hospital mortality was 6.1% for the COVID-19 group, 5.9% for the Influenza 2017/2018 group (p = 1.0), 11% and 11.2% for the season control groups. The respiratory virus diseases neither resulted in an overall treatment delay, nor did they cause an increase in STEMI mortality or incidence. The registry analysis demonstrated a prolonged door-to-balloon time during the COVID-19 pandemic.
format	article
author	S. Macherey M. M. Meertens C. Adler S. Braumann S. Heyne T. Tichelbäcker F. S. Nießen H. Christ I. Ahrens F. M. Baer F. Eberhardt M. Horlitz A. Meissner J. M. Sinning S. Baldus S. Lee
author_facet	S. Macherey M. M. Meertens C. Adler S. Braumann S. Heyne T. Tichelbäcker F. S. Nießen H. Christ I. Ahrens F. M. Baer F. Eberhardt M. Horlitz A. Meissner J. M. Sinning S. Baldus S. Lee
author_sort	S. Macherey
title	Impact of respiratory infectious epidemics on STEMI incidence and care
title_short	Impact of respiratory infectious epidemics on STEMI incidence and care
title_full	Impact of respiratory infectious epidemics on STEMI incidence and care
title_fullStr	Impact of respiratory infectious epidemics on STEMI incidence and care
title_full_unstemmed	Impact of respiratory infectious epidemics on STEMI incidence and care
title_sort	impact of respiratory infectious epidemics on stemi incidence and care
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ffc9d503b5354414a3ffb7a555fd7af2
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Impact of respiratory infectious epidemics on STEMI incidence and care

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