Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium

Various stages of tissue morphogenesis involve the contraction of epithelial surfaces. Here, the authors identify the Rab GTPase Rab35 as an essential component of this contractile process, which functions as a membrane ratchet to ensure unidirectional movement of intercalating cells.

Guardado en:

Detalles Bibliográficos
Autores principales:	Cayla E. Jewett, Timothy E. Vanderleest, Hui Miao, Yi Xie, Roopa Madhu, Dinah Loerke, J. Todd Blankenship
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ffd112e8fb114efa851ecacc98fe3c75
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ffd112e8fb114efa851ecacc98fe3c75
record_format	dspace
spelling	oai:doaj.org-article:ffd112e8fb114efa851ecacc98fe3c752021-12-02T15:38:54ZPlanar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium10.1038/s41467-017-00553-02041-1723https://doaj.org/article/ffd112e8fb114efa851ecacc98fe3c752017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00553-0https://doaj.org/toc/2041-1723Various stages of tissue morphogenesis involve the contraction of epithelial surfaces. Here, the authors identify the Rab GTPase Rab35 as an essential component of this contractile process, which functions as a membrane ratchet to ensure unidirectional movement of intercalating cells.Cayla E. JewettTimothy E. VanderleestHui MiaoYi XieRoopa MadhuDinah LoerkeJ. Todd BlankenshipNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cayla E. Jewett Timothy E. Vanderleest Hui Miao Yi Xie Roopa Madhu Dinah Loerke J. Todd Blankenship Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium
description	Various stages of tissue morphogenesis involve the contraction of epithelial surfaces. Here, the authors identify the Rab GTPase Rab35 as an essential component of this contractile process, which functions as a membrane ratchet to ensure unidirectional movement of intercalating cells.
format	article
author	Cayla E. Jewett Timothy E. Vanderleest Hui Miao Yi Xie Roopa Madhu Dinah Loerke J. Todd Blankenship
author_facet	Cayla E. Jewett Timothy E. Vanderleest Hui Miao Yi Xie Roopa Madhu Dinah Loerke J. Todd Blankenship
author_sort	Cayla E. Jewett
title	Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium
title_short	Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium
title_full	Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium
title_fullStr	Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium
title_full_unstemmed	Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium
title_sort	planar polarized rab35 functions as an oscillatory ratchet during cell intercalation in the drosophila epithelium
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ffd112e8fb114efa851ecacc98fe3c75
work_keys_str_mv	AT caylaejewett planarpolarizedrab35functionsasanoscillatoryratchetduringcellintercalationinthedrosophilaepithelium AT timothyevanderleest planarpolarizedrab35functionsasanoscillatoryratchetduringcellintercalationinthedrosophilaepithelium AT huimiao planarpolarizedrab35functionsasanoscillatoryratchetduringcellintercalationinthedrosophilaepithelium AT yixie planarpolarizedrab35functionsasanoscillatoryratchetduringcellintercalationinthedrosophilaepithelium AT roopamadhu planarpolarizedrab35functionsasanoscillatoryratchetduringcellintercalationinthedrosophilaepithelium AT dinahloerke planarpolarizedrab35functionsasanoscillatoryratchetduringcellintercalationinthedrosophilaepithelium AT jtoddblankenship planarpolarizedrab35functionsasanoscillatoryratchetduringcellintercalationinthedrosophilaepithelium
_version_	1718386090255056896

Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium

Ejemplares similares