Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5

Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5

The chemokine receptor CCR5 plays multiple roles in the immune system. Here, structures of Gi1 protein-coupled CCR5 with or without a chemokine bound and of the CCR5- chemokine MIP-1 α complex offer insight into the distinct binding modes of the ligands and into the mechanism of CCR5 activation.

Guardado en:
Detalles Bibliográficos
Autores principales: Hui Zhang, Kun Chen, Qiuxiang Tan, Qiang Shao, Shuo Han, Chenhui Zhang, Cuiying Yi, Xiaojing Chu, Ya Zhu, Yechun Xu, Qiang Zhao, Beili Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/ffd3451ed1a64d6295cce87f44f382f2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares