Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection.
NK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus infection (CHB), allowing them to kill hepatocytes bearing TRAIL receptors. In this stud...
Guardado en:
Autores principales: | Dimitra Peppa, Lorenzo Micco, Alia Javaid, Patrick T F Kennedy, Anna Schurich, Claire Dunn, Celeste Pallant, Gidon Ellis, Pooja Khanna, Geoffrey Dusheiko, Richard J Gilson, Mala K Maini |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ffd688712266402aa9a1b4de8190e233 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
EBV Positive Aggressive NK-Cell Leukemia
por: Ankitha Hebbar, et al.
Publicado: (2021) -
Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells
por: Tobias Straub, et al.
Publicado: (2018) -
Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma
por: Alexander H. Lee, et al.
Publicado: (2021) -
Current Perspectives on “Off-The-Shelf” Allogeneic NK and CAR-NK Cell Therapies
por: Erica L. Heipertz, et al.
Publicado: (2021) -
Immunosuppressant flavonoids from Scutellaria baicalensis
por: Nova Syafni, et al.
Publicado: (2021)