Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection.
NK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus infection (CHB), allowing them to kill hepatocytes bearing TRAIL receptors. In this stud...
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Autores principales: | , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/ffd688712266402aa9a1b4de8190e233 |
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