Adipose HuR protects against diet-induced obesity and insulin resistance

Adipose HuR protects against diet-induced obesity and insulin resistance

Human antigen R (HuR) is a RNA-binding protein. Here the authors investigate its role in adipose tissue and find that it protects mice from diet-induced obesity, prevents adipocyte hypertrophy, and promotes lipolysis, which may at least in part be due to HuR-dependent ATGL mRNA stability regulation...

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Autores principales: Jingyuan Li, Li Gong, Shaozhuang Liu, Yujie Zhang, Chunmei Zhang, Mi Tian, Huixia Lu, Peili Bu, Jianmin Yang, Changhan Ouyang, Xiuxin Jiang, Jiliang Wu, Yun Zhang, Qing Min, Cheng Zhang, Wencheng Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/ffdb9416baef42e0a24754e394971a46
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