Hyperphosphorylation of Tau Due to the Interference of Protein Phosphatase Methylesterase-1 Overexpression by MiR-125b-5p in Melatonin Receptor Knockout Mice

Melatonin has been indicated to ameliorate tau hyperphosphorylation in the pathogenesis of tau diseases, but the role of melatonin-receptor signal transduction has not been clearly discovered. In this study, we found intensive tau hyperphosphorylation in melatonin receptor knockout mice. Bielschowsk...

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Autores principales: Han Zhao, Lingyan Feng, Wei Zhong, Hongyan Zhen, Qingjia Chi, Xiang Wang
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
tau
Acceso en línea:https://doaj.org/article/ffe0ce70e19c4221b32c018f7a49f845
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