Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer

Losurdo et al analyze breast cancer-infiltrating T cells by single-cell technologies . The find that the extent of infiltration of a small subset of tissue-resident memory CD8+ T cells identify patients with improved survival, highlighting the importance of the specific T cell immune microenvironmen...

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Autores principales:	Agnese Losurdo, Caterina Scirgolea, Giorgia Alvisi, Jolanda Brummelman, Valentina Errico, Luca Di Tommaso, Karolina Pilipow, Federico Simone Colombo, Bethania Fernandes, Clelia Peano, Alberto Testori, Corrado Tinterri, Massimo Roncalli, Armando Santoro, Emilia Maria Cristina Mazza, Enrico Lugli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/ffe170fd97a449cfa53c352030435be9
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spelling	oai:doaj.org-article:ffe170fd97a449cfa53c352030435be92021-12-02T18:48:42ZSingle-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer10.1038/s42003-021-02595-z2399-3642https://doaj.org/article/ffe170fd97a449cfa53c352030435be92021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02595-zhttps://doaj.org/toc/2399-3642Losurdo et al analyze breast cancer-infiltrating T cells by single-cell technologies . The find that the extent of infiltration of a small subset of tissue-resident memory CD8+ T cells identify patients with improved survival, highlighting the importance of the specific T cell immune microenvironment.Agnese LosurdoCaterina ScirgoleaGiorgia AlvisiJolanda BrummelmanValentina ErricoLuca Di TommasoKarolina PilipowFederico Simone ColomboBethania FernandesClelia PeanoAlberto TestoriCorrado TinterriMassimo RoncalliArmando SantoroEmilia Maria Cristina MazzaEnrico LugliNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Agnese Losurdo Caterina Scirgolea Giorgia Alvisi Jolanda Brummelman Valentina Errico Luca Di Tommaso Karolina Pilipow Federico Simone Colombo Bethania Fernandes Clelia Peano Alberto Testori Corrado Tinterri Massimo Roncalli Armando Santoro Emilia Maria Cristina Mazza Enrico Lugli Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer
description	Losurdo et al analyze breast cancer-infiltrating T cells by single-cell technologies . The find that the extent of infiltration of a small subset of tissue-resident memory CD8+ T cells identify patients with improved survival, highlighting the importance of the specific T cell immune microenvironment.
format	article
author	Agnese Losurdo Caterina Scirgolea Giorgia Alvisi Jolanda Brummelman Valentina Errico Luca Di Tommaso Karolina Pilipow Federico Simone Colombo Bethania Fernandes Clelia Peano Alberto Testori Corrado Tinterri Massimo Roncalli Armando Santoro Emilia Maria Cristina Mazza Enrico Lugli
author_facet	Agnese Losurdo Caterina Scirgolea Giorgia Alvisi Jolanda Brummelman Valentina Errico Luca Di Tommaso Karolina Pilipow Federico Simone Colombo Bethania Fernandes Clelia Peano Alberto Testori Corrado Tinterri Massimo Roncalli Armando Santoro Emilia Maria Cristina Mazza Enrico Lugli
author_sort	Agnese Losurdo
title	Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer
title_short	Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer
title_full	Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer
title_fullStr	Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer
title_full_unstemmed	Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer
title_sort	single-cell profiling defines the prognostic benefit of cd39high tissue resident memory cd8+ t cells in luminal-like breast cancer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ffe170fd97a449cfa53c352030435be9
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Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer

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